教育背景 博士 2005.9-2010.7 山东大学 发育生物学 本科 2001.9-2005.7 山东大学 生物科学 工作经历 2010.10-2011.10 Sorbonne Université, IBPS-Developmental Biology Laboratory博士后 2010.7-2018.9 山东大学 讲师 2018.7 入选山东大学青年学者未来计划 2018.9-2019.12 山东大学 副教授 2020.1-2022.12 山东大学齐鲁青年学者特聘教授 2023.1至今 山东大学杰出中青年学者（第一层次）

1. 脊椎动物背腹轴形成母源调控的分子机制 2. 脊椎动物早期形态发生运动的分子机理 3. 人类遗传病相关基因的功能和分子机理

Zhang, C.1, Lu, T., Zhang, Y., Li, J., Tarique, I., Wen, F., Chen, A., Wang, J., Zhang, Z., Zhang, Y., Shi, D.-L., Shao, M.# (2021) Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish. Sci. Adv. 7, eabg4243 (2021). Shao, M.1#, Lu, T., Zhang, C., Zhang, Y., Kong, S., Shi, D.# (2020) Rbm24 controls poly(A) tail length and translation efficiency of crystallin mRNAs in the lens via cytoplasmic polyadenylation. Proc. Natl. Acad. Sci. USA. 117(13):7245-7254. Cheng, X.1, Shao, M.1, Li, J.1, Wang, Y., Qi, J., Xu, Z.#, Shi D.# (2017) Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish. Nat Commun. 8(1):1353. Xing, Y.1, Cheng, X., Li, Y., Zhang, C., Saquet, A., Liu, Y., Shao, M.#, Shi D.# (2018) Mutational analysis of dishevelled genes in zebrafish reveals distinct functions in embryonic patterning and gastrulation cell movements. PLoS Genet. 14(8):e1007551. Shao, M.1, Wang, M., Liu, Y., Ge, Y., Zhang, Y., Shi, D.# (2017) Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish. Development. 144(18):3361-3374. Shao, M.1, Liu, Z. Z., Wang, C. D., Li, H. Y., Carron, C., Zhang, H. W.#, & Shi, D. L.# (2009). Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos. Development, 136(12), 2121-2131. Sun, Y.1, Zhang, B., Luo, L., Shi, DL., Wang, H., Cui, Z., Huang, H., Cao, Y., Shu, X., Zhang, W., Zhou, J., Li, Y., Du, J., Zhao, Q., Chen, J., Zhong, H., Zhong, TP., Li, L., Xiong, JW., Peng, J., Xiao, W., Zhang, J., Yao, J., Yin, Z., Mo, X., Peng, G., Zhu, J., Chen, Y., Zhou, Y., Liu, D., Pan, W., Zhang, Y., Ruan, H., Liu, F.#, Zhu, Z.#, Meng, A.#; ZAKOC Consortium. (2020) Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome Res. 30(1):118–126. (Shao, M. is included in ZAKOC Consortium authors) Li, Y.1, Cheng, X.1, Lu, T.1, Shao, M#, Shi D.# (2021) Syne2b/Nesprin-2 Is Required for Actin Organization and Epithelial Integrity During Epiboly Movement in Zebrafish. Front. Cell Dev. Biol. 17(9):671887. Zhang, Y.1, Wang, Y., Yao, X., Wang, C., Chen, F., Liu, D., Shao, M.#, Xu, Z.# (2020) Rbm24a Is Necessary for Hair Cell Development Through Regulating mRNA Stability in Zebrafish. Front. Cell Dev. Biol. 17(8):604026. Li, J.1, Cheng, X.1, Zhang, C, Shi, D.#, Shao M.# (2021) The Adaptor Protein Lurap1 Is Required for Cell Cohesion during Epiboly Movement in Zebrafish. Biology (Basel) 10(12):1337. Zhang, C.1, Li, J., Tarique, I., Zhang, Y., Lu, T., Wang, J., Chen, A., Wen, F., Zhang, Z., Zhang, Y., Shao, M.# (2021) A Time-Saving Strategy to Generate Double Maternal Mutants by an Oocyte-Specific Conditional Knockout System in Zebrafish. Biology (Basel) 10(8):777. Liu, Y.1, Zhang, C., Zhang, Y., Lin, S., Shi D., Shao M.# (2018) Highly efficient genome editing using oocyte-specific zcas9 transgenic zebrafish. J. Genet. Genomics. 45(9):509-512. Cheng, X.1, Shao, M.#, Shi, D.# (2019) Collagen triple helix repeat containing 1a (Cthrc1a) regulates cell adhesion and migration during gastrulation in zebrafish. Exp Cell Res. 381(1):112-120. Shao, M.1#, Cheng, X., Liu, Y., Li, J., Shi, D.# (2017) Transplantation of Zebrafish Cells by Conventional Pneumatic Microinjector. Zebrafish. 15 (1), 73-76. Shao, M.1, Lin, Y., Liu, Z., Zhang, Y., Wang, L., Liu, C., & Zhang, H.# (2012). GSK-3 activity is critical for the orientation of the cortical microtubules and the dorsoventral axis determination in zebrafish embryos. PLoS One, 7(5), e36655. Zhang, Y.1,Shao, M.1, Wang, L., Liu, Z., Gao, M., Liu, C., & Zhang, H.# (2010). Ethanol exposure affects cell movement during gastrulation and induces split axes in zebrafish embryos. Int J Dev Neurosci, 28(4), 283-288.