教育背景 博士 2000.9-2005.6 山东大学 微生物学 本科 1996.9-2000.6 山东大学 微生物学 工作经历 2021.9-至今 山东大学 教授 2015.9-2021.8 山东大学 副教授 2009.6-2015.8 山东大学 讲师 2009.9-2010.8 瑞典Chalmers技术大学 博士后 2006.7-2009.5 河南天冠企业集团 博士后 2005.7-2006.6 江南大学 讲师

1. 代谢途径工程 2. 酵母碳代谢调控机制 3. 酵母对环境胁迫的耐受及应答机制

1.He, Y., Li, H., Chen, L., Zheng, L., Ye, C., Hou, J., Bao, X., Liu, W.,Shen, Y*.2021. Production of xylitol bySaccharomyces cerevisiaeusing waste xylose mother liquor and corncob residues. Microb Biotechnol. 5-year IF=6.559 2.Liang, Z., Wang, X., Bao, X., Wei, T., Hou, J., Liu, W.,Shen, Y*.2021. Newly identified genes contribute to vanillin tolerance inSaccharomyces cerevisiae. Microb Biotechnol, 14(2), 503-516. 5-year IF=6.559 3.Guo, W., Huang, Q., Feng, Y., Tan, T., Niu, S., Hou, S., Chen, Z., Du, Z.Q.*,Shen, Y.*,Fang, X*. 2020. Rewiring central carbon metabolism for tyrosol and salidroside production inSaccharomyces cerevisiae. Biotechnol Bioeng. 5-year IF= 4.630 4.Wu, M., Li, H., Wei, S., Wu, H., Wu, X., Bao, X., Hou, J., Liu, W.,Shen, Y*.2020. Simulating Extracellular Glucose Signals Enhances Xylose Metabolism in RecombinantSaccharomyces cerevisiae. Microorganisms, 8(1). IF= 4.128 5.Zheng, L., Wei, S., Wu, M., Zhu, X., Bao, X., Hou, J., Liu, W.,Shen, Y*. 2020. Improving Xylose Fermentation inSaccharomyces cerevisiaeby Expressing Nuclear-Localized Hexokinase 2. Microorganisms, 8(6). IF= 4.128 6.Wei, S., Bai, P., Liu, Y., Yang, M., Ma, J., Hou, J., Liu, W., Bao, X.,Shen, Y*.2019. A Thi2p Regulatory Network Controls the Post-glucose Effect of Xylose Utilization inSaccharomyces cerevisiae. Front Microbiol, 10, 1649. 5-year IF=6.320 7.Wei, S., Liu, Y., Wu, M., Ma, T., Bai, X., Hou, J.,Shen, Y.*,Bao, X. 2018. Disruption of the transcription factors Thi2p and Nrm1p alleviates the post-glucose effect on xylose utilization inSaccharomyces cerevisiae. Biotechnol Biofuels, 11, 112. 5-year IF= 6.485 8.Wang, X., Liang, Z., Hou, J.,Shen, Y.*,Bao, X*. 2017. The Absence of the Transcription Factor Yrr1p, Identified from Comparative Genome Profiling, Increased Vanillin Tolerance Due to Enhancements of ABC Transporters Expressing, rRNA Processing and Ribosome Biogenesis inSaccharomyces cerevisiae. 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Improvement of xylose fermentation in respiratory-deficient xylose-fermentingSaccharomyces cerevisiae. Metab Eng, 14(1), 9-18. doi: 10.1016/j.ymben.2011.12.001 (IF 8.201) 21.Shen, Y.1, Chen, X.1, Peng, B., Chen, L., Hou, J., & Bao, X*. (2012). An efficient xylose-fermenting recombinantSaccharomyces cerevisiaestrain obtained through adaptive evolution and its global transcription profile. Appl Microbiol Biotechnol, 96(4), 1079-1091. doi: 10.1007/s00253-012-4418-0 (IF 3.42) 22.Ji, L.1,Shen, Y.1, Xu, L., Peng, B., Xiao, Y., & Bao, X*. (2011). Enhanced resistance ofSaccharomyces cerevisiaeto vanillin by expression of lacA from Trametes sp. AH28-2. Bioresour Technol, 102(17), 8105-8109. doi: 10.1016/j.biortech.2011.06.057 (IF 5.651) 23.彭炳银,陈晓,沈煜*, &鲍晓明. (2011).不同启动子控制下木酮糖激酶的差异表达及其对酿酒酵母木糖代谢的影响.微生物学报, 51(7) :914-922. 24.Shen, Y., Zhang, Y., Ma, T., Bao, X.*, Du, F., Zhuang, G., & Qu, Y. (2008). Simultaneous saccharification and fermentation of acid-pretreated corncobs with a recombinantSaccharomyces cerevisiaeexpressing beta-glucosidase. Bioresour Technol, 99(11), 5099-5103. doi: 10.1016/j.biortech.2007.09.046 (IF 5.651)