2020年1月至今 山东大学药学院教授 2014年7月至2019年12月 山东大学药学院副教授 2009年7月至2014年6月 山东大学药学院讲师 2012年6月至2013年6月 美国亚利桑那大学药理毒理专业博士后 2004年9月至2009年7月 山东大学药学院药物化学博士 2000年9月至2004年7月 山东大学药学院药学学士

基于分子靶标的中药和天然药物药效物质研究 基于炎症失调的重大疾病的天然先导物发现和作用机制研究 创新药物研发和中药大品种“二次开发”

《Chinese Journal of Natural Medicines》青年编委 《TMR Modern Herbal Medicine》编委

1. Zhou, M.-X.; Li, G.-H.; Sun, B.; Xu, Y.-W.; Li, A.-L.; Li, Y.-R.; Ren, D.-M.; Wang, X.-N.; Wen, X.-S.; Lou, H.-X.;Shen, Tao*. Identification of novel Nrf2 activators fromCinnamomum chartophyllumH W Li and their potential application of preventing oxidative insults in human lung epithelial cells.Redox Biology,2018, 14, 154–163. 2. Wang, T.; Dai, F.; Li, G.-H.; Chen, X.-M.; Li, Y.-R.; Wang, S.-Q.; Ren, D.-M.; Wang, X.-N., Lou, H.-X.; Zhou, B.;Shen, Tao*.Trans-4,4′-dihydroxystilbene ameliorates cigarette smoke-induced progression of chronic obstructive pulmonary disease via inhibiting oxidative stress and inflammatory response.Free Radical Biology and Medicine,2020, 152, 525-539. 3. Wang, M.; Liu, C.-Y.; Wang, T.; Yu, H.-M.; Ouyang, S.-H.; Wu, Y.-P.; Gong, H.-B.; Ma, X.-H.; Jiao, G.-L.; Fu, L.-L.; Wu, Q.-S.; Kurihara, H.; Li, Y.-F.*;Shen, Tao*; He, R.-R*.(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis,Cell Death & Disease,2020, 11, 781. 4. Li, A.-L. #;Shen, Tao#; Wang, T.; Zhou, M.-X.; Wang, B.; Song, J.-T.; Zhang, P.-L.; Wang, X.-N.; Ren, D.-M.; Lou, H.-X.; Wang, X.-N*. Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis,Free Radical Biology and Medicine,2019, 141, 21–33. 5.Wu, X-Y; Wang, T.; Hu, H.-X.; Zhang, K.,; Zhao, Y.; Zhao, B.-B.; Lou, H.-X.; Wang, X.-N.; * Shen, T. * The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.Phytotherapy Research, 2022, 36, 1692–1707. 6. Li, Y.-R.; Li, G.-H.; Sun, L.; Li, L.; Liu, Y.; Kong, D.-G.; Wang, S.-Q.; Ren, D.-M.; Wang, X.-N.; Lou, H.-X.;Shen, Tao*.Ingredients fromLitsea garrettiias potential preventive agents against oxidative insult and inflammatory response,Oxidative Medicine and Cellular Longevity,2018, 7616852. 7. Yang, W.-J.; Chen, X.-M.; Wang, S.-Q., Hu, H.-X.; Cheng, X.-P.; Xu, L.-T.; Ren, D.-M.; Wang, X.-N.; Zhao, B.-B.; Lou, H.-X.;Shen, Tao*.4β-Hydroxywithanolide E from goldenberry (whole fruits of Physalis peruviana L.) as a promising agent against chronic obstructive pulmonary disease,Journal of Natural Products,2020, 83, 1217-1228. 8. Jin, T.-Y.; Li, S.-Q.; Jin, C.-R.; Shan, H.; Wang, R.-M.; Zhou, M.-X.; Li, A.-L.; Li, L.-Y.; Hu, S.-Y.;Shen, Tao*;Xiang, L.* Catecholic isoquinolines fromPortulaca oleraceaand their anti-inflammatory and beta(2)-adrenergic receptor agonist activity,Journal of Natural Products,2018, 81, 768–777. 9. Xu, L.-T.; Wang, T.; Fang, K.-L.; Zhao, Y.; Wang, X.-N.; Ren, D.-M.*;Shen, Tao*.The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB, Journal of Ethnopharmacology,2022, 283, 114694. 10. Hu, H.-X.; Xu, L.-T.; Gao, H.; Lv, H.; Huang, M.; Fang, K.-L.; Wang, S.-Q.; Zhao, B.-B.; Ren, D.-M.; Wang, X.-N.; Lou, H.-X.;Shen, Tao*. Chemical constituents from Physalis Calyx seu Fructus and their inhibitory effects against oxidative stress and inflammatory response,Planta Medica,2020, 86, 191-1203.