任冬梅
教授
个人简介
工作经历 1995年7月~至今:山东大学药学院,助教,讲师,副教授,教授 2017年3月~2019年3月:美国亚利桑那大学,访问学者 2015年9月~2016年9月:国家药监总局药品审评中心,山东挂职团队 2009年2月~2010年9月:美国亚利桑那大学,博士后 2005年5月~11月:国家药监总局药品审评中心,中药药学外聘审评员 学习经历 1988年9月~1992年7月:山东医科大学药学系,获学士学位 1992年9月~1995年7月:山东中医药大学,获硕士学位 2003年9月~2007年7月:山东大学药学院,获博士学位
研究领域
影响Nrf2-Keap1信号通路表达的天然产物分离及机制研究 天然产物用于化学预防及作用机制 中药新药产品开发与技术研究
近期论文
1. Huaran Zhang, Shuqi Wang, Qingying Liu, Hao Zheng, Xiaoqing Liu, Xiaoning Wang, Tao Shen, Dongmei Ren*. Dracomolphin A-E, new lignans fromDracocephalum moldavica. Fitoterapia. 150 (2021), 104841. 2.Jinxia Wang,Xiaoqing Liu, Hao Zheng, Qingying Liu,Huaran Zhang, Xiaoning Wang, Tao Shen, Shuqi Wang, DongmeiRen*.Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.Chem. Biol. Interact.331 (2020), 109279. 3. HuaranZhang, Lintao Xu, Xiaoqing Liu, Jiangjiang Fan, Xiaoning Wang, Tao Shen, Shuqi Wang, Dongmei Ren*. Dracomolphesin A-E, five 3,4-seco-phenylpropanoids with Nrf2 inducing activity fromDracocephalum moldavica. Chin. Chem. Lett.31(2020), 1259-1262. 4. Huaran Zhang, Ming Li, Miaomiao Wang, Xaioning Wang, Tao Shen, Shuqi Wang, Dongmei Ren*. Antioxidant flavan derivatives from the leaves ofMorus alba. Phytochem. Lett. 29 (2019), 84-90. 5. Wenjing Yang, Jixiang He, Mingxing Zhou, Ming Huang, Shuqi Wang, Xiaoning Wang, Hongxiang Lou, Dongmei Ren*, Tao Shen*.An isopentenyl-substituted flavonoid norartocarpin activates Nrf2 signaling pathway and prevents oxidative insults in human lung epithelial cells. Free Radical Research. 53 (2019), 348-358. 6. Lan Chen, Xuewei Wu, Tao Shen, Xiaoning Wang, Shuqi Wang, Jinxia Wang, Dongmei Ren*. Protective effects of ethyl gallate on H2O2-induced mitochondrial dysfunction in PC12 cells. Metab. Brain Dis. 34 (2019), 545-555. 7. Jinxia Wang, Haizhen Li, Xiaoning Wang, Tao Shen, SHuqi Wang, Dongmei Ren*. Alisol B-23-acetate, a tetracyclic triterpenoid isolated fromAlisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway. Biochem. Biophys. Res. Commun. 505 (2018), 1015-1021. 8. TaoShen, Haizhen Li, Ailing Li, Yanru Li, Xiaoning Wang, Dongmei Ren*. (2018) Homoeriodictyol protects human endothelial cells against oxidative insults through mitochondrial dysfunction. Vasc. Pharmacol. 109 (2018), 72-82. 9. Zhuqing Huang, Guotao Yang, Tao Shen, Xiaoning Wang, Haizhen Li, Dongmei Ren*. Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells. Biomed. Pharmacother. 89 (2017), 623-631. 10. Lijuan Zhao, Qing Wen, GuotaoYang, ZHuqing Huang, Tao Shen, Haizhen Li, DongmeiRen*.Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway. Phytomedicine. 23 (2016), 114-122.