教育经历 2003/09-2008/06，山东大学，生命科学学院，博士学位 1994/09-1998/06，山东大学，生命科学学院，学士学位 研究工作经历 2008/07-今，山东大学国家糖工程技术研究中心/微生物技术国家重点实验室 2011/01-2012/07，美国佛罗里达大学，微生物与细胞科学系，访问学者

真菌底盘细胞的分子生物学和合成生物学研究、微生物酶资源的挖掘与鉴定。主要研究内容包括：（1）真菌纤维素酶合成与分泌调控机制的研究及遗传改造；（2）微生物酶资源的挖掘、功能鉴定与改造；（3）酶蛋白产物的真菌细胞工厂的设计、构建与适配性优化。

1.Zhang X, Hu Y, Liu G, Liu M, Li Z, Zhao J, Song X, Zhong Y, Qu Y, Wang L, Qin Y*. The complex Tup1-Cyc8 bridges transcription factor ClrB and putative histone methyltransferase LaeA to activate the expression of cellulolytic genes. Mol Microbiol. 2022 Jan 24. doi: 10.1111/mmi.14885. 2.Zhao K, Liu Z, Li M, Hu Y, Yang L, Song X, Qin Y*. Drafting Penicillium oxalicum calcineurin-CrzA pathway by combining the analysis of phenotype, transcriptome, and endogenous protein-protein interactions. Fungal Genet Biol. 2022 Jan;158:103652. doi: 10.1016/j.fgb.2021.103652. 3.Hu Y, Li M, Liu Z, Song X, Qu Y, Qin Y*. Carbon catabolite repression involves physical interaction of the transcription factor CRE1/CreA and the Tup1-Cyc8 complex in Penicillium oxalicum and Trichoderma reesei. Biotechnol Biofuels. 2021 Dec 24;14(1):244. 4.Haiyan Chen, Xuezhi Li, Shaoyang Yu, Yuqi Qin*, Yinbo Qu, Jian Zhao*. Potassium permanganate assisted organosolv pretreatment enhances enzymatic hydrolysis of corn stover. GCB Bioenergy. 2021 13:666-678. 5.Hu Y, Zhao K, Qu Y, Song X, Zhao J, Qin Y*. Penicillium oxalicum S-adenosylmethionine synthetase is essential for the viability of fungal cells and the expression of genes encoding cellulolytic enzymes. Fungal Biology. 2021 125(1):1-11 6.Zhang X, Li M, Zhu Y, Yang L, Li Y, Qu J, Wang L, Zhao J, Qu Y, Qin Y*. Penicillium oxalicum putative methyltransferase Mtr23B has similarities and differences with LaeA in regulating conidium development and glycoside hydrolase gene expression. 2020 Oct;Fungal Genet Biol. 143:103445. 7.Pan Y, Gao L, Zhang X, Qin Y*, Liu G*, Qu Y. The Role of Cross-Pathway Control Regulator CpcA in the Growth and Extracellular Enzyme Production of Penicillium oxalicum. Curr Microbiol. 2020 Jan 77(1):49-54. 8.Li Y, Hu Y, Zhao K, Pan Y, Qu Y, Zhao J, Qin Y*. The Indispensable Role of Histone Methyltransferase PoDot1 in Extracellular Glycoside Hydrolase Biosynthesis of Penicillium oxalicum. Front Microbiol. 2019 Nov 10:2566. 9.Zhu Z, Qu J, Yu L, Jiang X, Liu G, Wang L, Qu Y, Qin Y*. Three glycoside hydrolase family 12 enzymes display diversity in substrate specificities and synergistic action between each other. Mol Biol Rep. 2019 Oct 46(5):5443-5454. 10.Li Y, Hu Y, Zhu Z, Zhao K, Liu G, Wang L, Qu Y, Zhao J, Qin Y*. Normal transcription of cellulolytic enzyme genes relies on the balance between the methylation of H3K36 and H3K4 in Penicillium oxalicum. Biotechnol Biofuels. 2019-Aug. 12:198.