1989.9-1993.7 聊城师范学院化学系化学教育专业，获理学学士学位 1996.9-1999.7 中国科学技术大学分析化学专业，获理学硕士学位 1999.9-2002.7 中国科学技术大学分析化学专业，获理学博士学位 2002.9-2004.8 清华大学化学系药物研究所做博士后工作（助研） 2007.10-2008.10 美国康奈尔大学（Cornell University）食品科学技术系访问学者 2015.2-2015.11 美国纽约州立大学布法罗分校（University at Buffalo）药学系访问学者 1993.9-1996.9 济南职工科技大学基础部任教 2004.8至今在山东大学药学院药物分析研究所任教，2006.9晋升为副教授

中药质量控制及评价方法研究(包括指纹图谱构建方法及相关分析，谱效关系研究以及中药现代鉴别方法研究等)，蛋白质组学及代谢组学分析。

1.Yue Sun, Meng Yuan, Xiaoyan Liu, Mei Su, Linlin Wang, Yingzi Zeng, Hengchang Zang,Lei Nie*,A sample selection method specific to unknown test samples for calibration and validation sets based on spectra similarity,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 258: 119870. 2. Yue Sun, Meng Yuan, Xiaoyan Liu, Mei Su, Linlin Wang, Yingzi Zeng, Hengchang Zang,Lei Nie*，Comparative analysis of rapid quality evaluation of Salvia miltiorrhiza (Danshen) with Fourier transform near-infrared spectrophotometer and micro near-infrared spectrophotometer,Microchemical Journal，2020，159：105492. 3. Xiaoyan Liu, Hui Zhang, Mei Su, Yue Sun, Hongming Liu, Hengchang Zang*,Lei Nie*,Comprehensive quality evaluation strategy based on non-targeted, targeted and bioactive analyses for traditional Chinese medicine: Tianmeng oral liquid as a case study,Journal of Chromatography A, 2020, 1620: 460988. 4.刘肖雁，姜文文，蒋海强，苏美，孙越，臧恒昌，曾英姿，聂磊*，基于“谱-效-代”关联的参枝苓口服液质量标志物的初步研究，中草药，2019，50（19）：4603-4612. 5. Xiaoyan Liu, Wenwen Jiang, Mei Su, Yue Sun, Hongming Liu*,Lei Nie*, Hengchang Zang, Quality evaluation of traditional Chinese medicines based on fingerprinting,Journal of separation science, 2019, 1-12, DOI: 10.1002/jssc.201900365. 6. Wenwen Jiang, Yue Sun, Xiaoyan Liu, Mei Su, Hengchang Zang, Yingzi Zeng ,Hongming Liu*,Lei Nie*, Rapid quality evaluation of Shenzhiling oral liquid by attenuated total reflectance-infrared spectroscopy with chemometrics,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 223: 117-324. 7. Wenwen Jiang, Xiaoyan Liu, Mei Su, Hengchang Zang, Yingzi Zeng,Lei Nie*, Chromatographic fingerprint based on serially coupled columns combined with multiple- component quantitation with a single reference standard for quality evaluation of Shen–Zhi–Ling oral liquid,Analytical Methods, 2019,11: 367-374. 8. Jie Zhou,Lei Nie(co-first authors), Bin Zhang, Guizheng Zou*, Spectrum-Resolved Triplex-Color Electrochemiluminescence Multiplexing Immunoassay with Highly-Passivated Nanocrystals as Tags,Analytical Chemistry, 2018, 90 : 12361-12365. 9. Zhongyu Sun , Jiayue Wang,Lei Nie*, Lian Li, Dawei Cao, Jiajin Fan, Haiyan Wang, Ruichen Liu, Yinran Zhang, Hengchang Zang*, Calibration transfer of near infrared spectrometers for the assessment of plasma ethanol precipitation process,Chemometrics and Intelligent Laboratory Systems, 2018,181: 64-71. 10. Xiaomeng Shen, Shichen Shen, Jun Li, Qiang Hu,Lei Nie, Chengjian Tu, Xue Wang, David J. Poulsen, Benjamin C. Orsburn, Jianmin Wang, and Jun Qu*，IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts,PNAS, May 9, 2018. 201800541. https://doi.org/10.1073/ pnas.1800541115.