教育背景 医学博士 2003.4-2007.3 日本千叶大学（Chiba University）医学院 理学硕士 2000.4-2002.3 日本熊本大学（Kumamoto University）自然科学研究科 农学士 1992.9-1997.6 中国农业大学 动物医学院 工作经历 2018.5-现在 山东大学生命科学学院 教授，博导 2011.8-2018.4 山东大学医学院 教授，博导 2007.4-2011.8 美国密西根大学（University of Michigan）医学院 博士后 2002.4-2007.3 日本理化学研究所 (RIKEN) 生命医科学研究中心（IMS）JRA 1999.4-2002.3 日本国立水俣病研究中心(NIMD） 特别研究员

干细胞分化的表观遗传学调控 疾病发生发展的表观遗传学调控 哺乳动物胚胎发育的分子机制

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Zhang X, Yang Y, Li D, Wu Z, Liu H, Zhao Z, Zhu H, Xie F, Li X*., MOF negatively regulates estrogen receptor α signaling via CUL4B-mediated protein degradation in breast cancer. Front Oncol. 2022; 12:868866. 6. Wang M, Liu H, Zhang X, Zhao W, Lin X, Zhang F, Li D, Xu C, Xie F, Wu Z, Yang Q, Li X*., Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α. Front Cell Dev Biol. 2021; 9:718707. 7. Wang M, Liu H, Zhang X, Zhao W, Li D, Xu C, Wu Z, Xie F, Li X*., Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1. J Cell Physiol. 2021; 236(9):6559-6570. 8. Yu L, Wang M, Yang Y, Xu F, Zhang X, Xie F, Gao L, Li X*., Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways. PLoS Comput Biol. 2021; 17(2): e1008696. 9. 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