教育背景 博士2006-2011 山东大学 微生物学 学士2002-2006 山东大学 生物技术 工作经历 2022.09-至今 山东大学微生物技术国家重点实验室 教授 2018.06-2022.08 山东大学微生物技术国家重点实验室 副研究员 2016.07-2018.05 山东大学海洋研究院 副研究员 2012.02-2015.12 山东大学化学与化工学院 博士后

1.海洋来源有机碳降解酶的挖掘、功能及结构分析 2.海洋中难培养微生物的富集培养及生理与遗传特征分析

1. Jiang WX#,Li PY#*, Chen XL, Zhang YS, Wang JP, Wang YJ, Sheng Q, Sun ZZ, Qin QL, Ren XB, Wang P, Song XY, Chen Y, Zhang YZ*. A pathway for chitin oxidation in marine bacteria. Nat Commun, 2022, 13:5899 2. Qin QL#, Wang ZB#, Cha QQ, Liu SS, Ren XB, Fu HH, Sun ML, Zhao DL, McMinn A, Chen Y, Chen XL, Zhang YZ*,Li PY*. Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level. Environ Microbiol, 2022, 24:98-109 3. Zhang Y#, Ding HT#, Jiang WX, Zhang X, Cao HY, Wang JP, Li CY, Huang F, Zhang XY, Chen XL, Zhang YZ*,Li PY*.Active site architecture of an acetyl xylan esterase indicates a novel cold adaptation strategy. J Biol Chem, 2021, 297:100841 4. Wang Y#,Li PY#, Zhang Y, Cao HY, Wang YJ, Li CY, Wang P, Su HN, Chen Y, Chen XL*, Zhang YZ*. 3,6-anhydro-L-galactose dehydrogenaseVvAHGD is a member of a new aldehyde dehydrogenase family and catalyzes by a novel mechanism with conformational switch of two catalytic residues cysteine 282 and glutamate 248. J Mol Biol, 2020, 432:2186-2203 5.Wang YJ, Jiang WX, Zhang YS, Cao HY, Zhang Y, Chen XL, Li CY, Wang P, Zhang YZ, Song XY*, Li PY*. Structural insight into chitin degradation and thermostability of a novel endochitinase from the glycoside hydrolase Family 18. Front Microbiol, 2019, 10:2457 6. Chen XL#, Zhao F#, Yue YS, Zhang XY, Zhang YZ,Li PY*. A new group of modular xylanases in glycoside hydrolase family 8 from marine bacteria. Appl Environ Microbiol, 2018, 84: e01785-18 7.Li PY#, Zhang Y#, Xie BB*, Zhang YQ, Hao J, Wang Y, Wang P, Li CY, Qin QL, Zhang XY, Su HN, Shi M, Zhang YZ, Chen XL*. Structural and mechanistic insights into the improvement of the halotolerance of a marine microbial esterase by increasing intra- and interdomain hydrophobic interactions.Appl Environ Microbiol, 2017, 83: e01286~17 8.Li PY#, Yao QQ#, Wang P, Zhang Y, Li Y, Zhang YQ, Hao J, Zhou BC, Chen XL*, Shi M, Zhang YZ, Zhang XY*.A novel subfamily esterase with a homoserine transacetylase-like fold but no transferase activity. Appl Environ Microbiol, 2017, 83：e00131~17 9.Li PY, Chen XL, Ji P, Li CY, Wang P, Zhang Y, Xie BB, Qin QL, Su HN, Zhou BC, Zhang YZ, Zhang XY*. Interdomain hydrophobic interactions modulate the thermostability of microbial esterases from the hormone-sensitive lipase family.J Biol Chem, 2015, 290: 11188~11198 10.Li PY, Ji P, Li CY, Zhang Y, Wang GL, Zhang XY, Xie BB, Qin QL, Chen XL, Zhou BC, Zhang YZ*. Structural basis for dimerization and catalysis of a novel esterase from the GTSAG motif subfamily of the bacterial hormone-sensitive lipase family.J Biol Chem, 2014, 289: 19031~19041 11.Li PY, Xie BB*, Zhang XY, Qin QL, Dang HY, Wang XM, Chen XL, Yu J, Zhang YZ*. Genetic structure of three fosmid-fragments encoding 16S rRNA genes of the Miscellaneous Crenarchaeotic Group (MCG): implications for physiology and evolution of marine sedimentary archaea.Environ Microbiol, 2012, 14: 467~479