教育背景 博士起止时间：1994-1997 毕业院校：山东大学 专业：微生物学 硕士起止时间：1991-1994 毕业院校：山东大学 专业：微生物学 学士起止时间：1987-1991 毕业院校：山东大学 专业：微生物学 工作经历 1997－今 山东大学微生物技术国家重点实验室 教授 2006 美国加州大学洛杉矶分校 医学院 访问学者 2002- 2003 英国谢菲尔德大学 生化与分子生物学系 访问学者

1. 生物质资源的转化利用及相关酶的催化机制 2. 结晶纤维素降解机制和细菌运动的分子机制 3. 高等真菌活性物质的发掘和综合利用

1. Lijuan Gao, Yahong Tan, Weican Zhang, Qingsheng Qi andXuemei Lu*,Cytophaga hutchinsoniiSprA and SprT are essential components of the type IX secretion system required for Ca2+ acquisition, cellulose degradation, and cell motility,Frontiers in Microbiology, 2021. 12: p. 628555. 2. Dong Zhao, Ying Wang, Sen Wang, Weican Zhang, Qingsheng Qi,Xuemei Lu*.A Disulfide Oxidoreductase CHU_1165 is Essential for cellulose degradation by affecting outer membrane proteins inCytophaga hutchinsonii,Applied and Environmental Microbiology,2020, 86(8): e02789-19 3. Lijuan Gao, Zhiwei Guan, Peng Gao, Weican Zhang, Qingsheng Qi,Xuemei Lu*.Cytophaga hutchinsoniigldN, Encoding a core component of the type IX secretion system, is essential for ion assimilation, cellulose degradation, and cell motility.Applied and Environmental Microbiology. 2020,86(11): e00242-20 4. Xifeng Wang, Dong Zhao, Lijuan Gao, Weican Zhang,Xuemei Lu*. Cage-like polyhedrons of DegQ fromCytophaga hutchinsoniishow stable proteolytic activity and strong chaperone activity,Biochemical Engineering Journal,2020, 159: 107585 5.Sen Wang, Dong Zhao, Weican Zhang,Xuemei Lu*.Identification of a cell-surface protein involved in glucose assimilation and disruption of the crystalline region of cellulose byCytophaga hutchinsonii.Journal of Industrial Microbiology & Biotechnology,2019, 46(11): 1479–1490. 6. Zhiwei Guan, Ying Wang, Lijuan Gao, Weican Zhang andXuemei Lu*. Effects of the histone-like protein HU on cellulose degradation and biofilm formation ofCytophaga hutchinsonii.Applied Microbiology and Biotechnology,2018,102(15): 6593–6611 7. Xifeng Wang, Zhiquan Wang, Xinfeng Bai, Yue Zhao, Weican Zhang andXuemei Lu*. Deletion of a Gene Encoding a Putative Peptidoglycan-Associated Lipoprotein Prevents Degradation of the Crystalline Region of Cellulose inCytophaga hutchinsonii.Frontiers in Microbiology,2018, 9: 632-644 8. Xinfeng Bai, Xifeng Wang, Sen Wang, Xiaofei Ji, Zhiwei Guan, Weican Zhang andXuemei Lu*, Functional Studies of β-Glucosidases ofCytophaga hutchinsoniiand Their Effects on Cellulose Degradation,Frontiers in Microbiology,2017, 8:140. doi: 10.3389/fmicb.2017.00140 9.Sen Wang, Dong Zhao, Xinfeng Bai, Weican Zhang,Xuemei Lu*, Identification and Characterization of a Large Protein Essential for Degradation of the Crystalline Region of Cellulose byCytophaga hutchinsonii,Applied and Environmental Microbiology,2017, 83(1): e02270-16 10. Cong Zhang, Xifeng Wang, Weican Zhang, Yue Zhao,Xuemei Lu*, Expression and characterization of a glucose-tolerant β-1,4-glucosidase with wide substrate specificity fromCytophaga hutchinsonii,Applied Microbiology and Biotechnology,2017, 101(5): 1919–1926 11.Cong Zhang, Weican Zhang,Xuemei Lu*, Expression and characteristics of a Ca2+-dependent endoglucanase fromCytophaga hutchinsonii,Applied Microbiology and Biotechnology,2015, 99(22): 9617-9623 12. Zhe Li, Cong Zhang, Sen Wang, Jing Cao, Weican Zhang andXuemei Lu*,A new locus inCytophaga hutchinsoniiinvolved in colony spreading on agar surfaces and individual cell gliding,FEMS Microbiology Letters,2015, 362(14): 1-8 13.Ying Wang, Zhiquan Wang, Jing Cao, Zhiwei Guan andXuemei Lu*,FLP-FRT-based method to obtain unmarked deletions of CHU_3237 (porU) and large Genomic fragments ofCytophaga hutchinsonii,Applied and Environmental Microbiology,2014, 80 (19 ): 6037-6045 14.Xiaofei Ji, Ying Wang, Cong Zhang, Xinfeng Bai, Weican Zhang,Xuemei Lu*, A novel outer membrane protein involved in cellulose and cellooligosaccharide degradation byCytophaga hutchinsonii,Applied and Environmental Microbiology,2014, 80 (15): 4511-4518 15. Cong Zhang, Ying Wang, Zhe Li, Xiangru Zhou, Weican Zhang, Yue Zhao ,Xuemei Lu*, Characterization of a multi-function processive endoglucanase CHU_2103 fromCytophaga hutchinsonii,Applied Microbiology and Biotechnology,2014, 98 (15) : 6679-6687 联系我们