靳岚 照片

靳岚

教授

所属大学: 山东大学

所属学院: 国家糖工程技术研究中心

邮箱:
lanjin@sdu.edu.cn

个人主页:
http://www.glycoeng.sdu.edu.cn/info/1058/3501.htm

个人简介

教育经历 1999-2003年,辽宁大学化学院,应用化学专业,获理学学士学位; 2003-2007年,英国University of Edinburgh化学院,生物物理化学专业,获理学博士学位。 工作经历 2007-2008年,英国University of Edinburgh化学院,生物核磁组,博士后研究员;英国BBSRC方法学改进项目,NMR定量研究糖与蛋白质相互作用; 2008年8月至今,山东大学国家糖工程技术研究中心,依次聘为副教授、教授,主要从事生物核磁共振波谱方法开发、低分子肝素药物结构表征、糖与蛋白质相互作用的构效关系研究。主持国家及省部级科研项目及企业委托研发项目多项,已发表SCI收录论文40余篇。

研究领域

NMR解析寡糖分子空间结构;寡糖与多肽的相互作用及构效关系。

近期论文

1. Qingqing Chen, Xiaohui Xu, Shaoshuai Xie, Anran Sheng, Naihan Han, Zhenyu Tian, Xiaowei Wang, Fuchuan Li, Robert J. Linhardt, Fuming Zhang, Lan Jin*, Qunye Zhang*, Lianli Chi *, Improving impact of heparan sulfate on the endothelial glycocalyx abnormalities in atherosclerosis as revealed by glycan-protein interactome, Carbohydrate Polymers, 2024, 330, 121834. 2. Deling Shi, Anran Sheng, Changkai Bu, Zizhe An, Xueying Cui, Xiaojun Sun, Hongmei Li, Fuming Zhang, R.J. Linhardt, Tianji Zhang*, Lan Jin*, Lianli Chi*, A cluster sequencing strategy to determine the consensus affinity domains in heparin for its binding to specific proteins, Analytical Chemistry, 2022, 94, 13987. 3. Xiang Zhou, Yuanyuan Wang, Wei Zheng, Guangxiu Deng, Fuyi Wang*, Lan Jin*, Characterizing heparin tetrasaccharides binding to Amyloid-beta peptide, Frontiers in Molecular Biosciences, 2022, 9, 824146. 4. Anran Sheng, Qingqing Chen, Mengqi Yu, Ruiqi Xiao, Tianji Zhang, Zhiyu Wang, Robert J. Linhardt, Xiaojun Sun*, Lan Jin*, and Lianli Chi*,Coupling Liquid Chromatography and Tandem Mass Spectrometry to Electrophoresis for In-Depth Analysis of Glycosaminoglycan Drugs: Heparin and the Multicomponent Sulodexide, Analytical Chemistry, 2021, 93, 1433. 5. Shaoshuai Xie, Yudong Guan, Peipei Zhu, Fei Li, Mengqi Yu, Robert J. Linhardt, Lianli Chi*, Lan Jin*. Preparation of low molecular weight heparins from bovine and ovine heparins using nitrous acid degradation, Carbohydrate Polymers, 2018, 197, 83. 6. Lan Jin, Miloš Hricovíni, Jon A Deakin, Malcolm Lyon, Dušan Uhrín. Residual dipolar coupling investigation of a heparin tetrasaccharide confirms the limited effect of flexibility of the iduronic acid on the molecular shape of heparin, Glycobiology, 2009, 19, 1185. 7. Lan Jin, Tran N. Pham, Dušan Uhrín. Measurement of 1H-1H Residual Dipolar Coupling Constants for Structural Studies of Medium Size Molecules, ChemPhysChem, 2007, 8, 1228. 8. Lan Jin, Perdita E. Barran, Jon A. Deakin, Malcolm Lyon, Dušan Uhrín. Conformation of glycosaminoglycans by ion mobility mass spectrometry and molecular modelling, PhysChemChemPhys, 2005, 7, 3464.