侯丙凯
教授
个人简介
教育背景 博士后2003-2005英国约克大学生物系植物分子生物学 博士1997-2000中国科学院遗传研究所植物分子遗传学 硕士1988-1991山东大学生物系植物生理学 本科1981-1985曲阜师范大学生物系生物学 工作经历 2003年-至今山东大学生命科学学院,植物发育与逆境适应生物学教育部重点实验室,教授,博士生导师 1997-2002年山东大学生命科学学院副教授 1991-1996年山东大学生物系讲师
研究领域
1.植物激素糖基化修饰与生长发育。激素的糖基化修饰是激素代谢修饰的一种重要方式,能够影响激素活性,调节激素动态平衡,控制植物生长发育。本方向将以拟南芥、水稻、玉米等为实验材料,通过遗传学、分子生物学、生物化学等研究手段,紧紧围绕植物激素这一重要方向,克隆与植物激素相关的糖基转移酶基因,鉴定酶的糖基化修饰活性,研究糖基转移酶基因在植物体内调节激素活性和植物生长发育的分子机制。 2.植物小分子糖基化与植物抗逆。植物的非生物胁迫反应中涉及大量的分子糖基化修饰过程,本方向将重点围绕植物抗盐、抗旱、抗高低温、抗病等胁迫抗性,克隆与这些抗性相关的糖基转移酶基因,研究它们与胁迫抗性的关系和信号通路,为重要经济作物的抗逆育种奠定理论基础和技术基础。 3.植物分子糖基化与能源生物质的改良。植物来源的木质纤维素通过纤维素降解和发酵可产生化石能源的替代品—乙醇,生物质能源对于解决当前的能源危机具有重要意义。本研究方向将围绕细胞壁木质纤维素的改造,克隆鉴定与木质素、纤维素合成有关的糖基转移酶基因,研究这些基因对于植物木质素、纤维素等物质合成的调节作用,提高植物来源的木质纤维素的发酵效率,创造新型高效的能源生物质。
近期论文
1. Huang XX#, Wang Y#, Lin JS, Chen L, Li YJ, Liu Q, Wang GF, Xu F, Liu LJ, Hou BK*. A novel pathogen-responsive glycosyltransferase UGT73C7 mediates the redirection of phenylpropanoid metabolism and promotes SNC1-dependent Arabidopsis immunity. Plant Journal, 2021, 107: 149–165 2. Chen L, Huang XX, Zhao SM, Xiao DW, Xiao LT, Tong JH, Wang WS, L YJ, Ding ZJ, Hou BK. IPyA glucosylation mediates light and temperature signaling to regulate auxin-dependent hypocotyl elongation in Arabidopsis. PNAS, 2020,117:6910-6917(该成果获得美国华盛顿大学Lucia C. Strader教授的专题介绍和评述,见PNAS,117:7558–7560) 3. Chen L, Wang WS, Wang T, Meng XF, Chen TT, Huang XX, Li YJ, Hou BK*. Methyl salicylate glucosylation regulates plant defense signalling and systemic acquired resistance. Plant Physiology. 2019, 180:2167-2181(该成果获得比利时根特大学Amna Mhamdi教授的专题介绍和评述,见Plant Physiology,180:1784-1785) 4. Huang XX, Zhu GQ, Liu Q, Chen L, Li YJ, Hou BK*. Modulation of plant salicylic acid-associated immune responses via glycosylation of dihydroxybenzoic acids. Plant Physiology. 2018, 176 : 3103-3119 5. Li P#, Li YJ#, Zhang FJ, Zhang GZ, Jiang XY, Yu HM, Hou BK*. The Arabidopsis UDP-glycosyltransferases UGT79B2 and 79B3, contribute to cold, salt and drought stress tolerance via modulating anthocyanin accumulation. The Plant J, 2017, 89:85-103 6. Lin JS, Huang XX, Li Q, Cao YP, Bao Y, Meng XF, Li YJ, Fu CX, Hou BK* UDP-glycosyltransferase 72B1 catalyzes the glucose conjugation of monolignols and is essential for the normal cell wall lignification in Arabidopsis thaliana. The Plant J, 2016, 88: 26-42 7. Wang B, Jin SH, Hu HQ, Sun YG, Wang YW, Han P, Hou BK*. UGT87A2, an Arabidopsis glycosyltransferase, regulates flowering time via FLOWERING LOCUS C. New Phytologist, 2012, 194: 666-675. 8. Wang YW, Wang WC, Jin SH, Wang J, Wang B, Hou BK*. Over-expression of a Putative Poplar Glycosyltransferase Gene, PtGT1, in Tobacco Increases Lignin Content and Causes Early Flowering. Journal of Experimental Botany. 2012, 63:2799-2808 9. Wang T, Ma YQ, Huang XX, Mu TJ, Li YJ, Li XK, Liu X, Hou BK*(2021)Overexpression of OsUGT3 enhances drought and salt tolerance through modulating ABA synthesis and scavenging ROS in rice. Environmental and Experimental Botany, 192: article 104653. 10. Wang J, Ma XM, Kojima M, Sakakibara H, Hou BK*. N-Glucosyltransferase UGT76C2 is Involved in Cytokinin Homeostasis and Cytokinin Response in Arabidopsis thaliana. Plant and Cell Physiology. 2011, 52(12): 2200-2213 11. Zhang GZ, Jin SH, Jiang XY, Dong RR, Li P, Li YJ, Hou BK*. Ectopic expression of UGT75D1, a glycosyltransferase preferring indole-3-butyric acid, modulates cotyledon development and stress tolerance in seed germination of Arabidopsis thaliana. Plant Molecular Biology, 2016, 90:77-93 12. Li YJ, Li P, Wang T, Zhang FJ, Huang XX, Hou BK*. The maize secondary metabolism glycosyltransferase UFGT2 modifies flavonols and contributes to the plant acclimation to abiotic stresses. Annals of Botany, 2018, 122: 1203-1217 13. Liu Q, Dong GR, Ma YQ, Zhao SM, Liu X, Li XK, Li YJ, Hou BK* (2021) Rice glycosyltransferase gene UGT85E1 is involved in drought stress tolerance through enhancing abscisic acid response. Frontiers Plant Sci. 12: article 790195 14. Li YJ#, Wang B#, Dong RR, Hou BK*. AtUGT76C2, an Arabidopsis cytokinin glycosyltransferase is involved in drought stress adaptation. Plant Science, 2015,236:157-167 15. Li YJ, Li P, Wang Y, Dong RR, Yu HM, Hou BK*. Genome-wide identification and phylogenetic analysis of Family-1 UDP glycosyltransferases in maize (Zea mays). Planta, 2014,239:1265-1279 16. Jin SH#, Ma XM#, Han P, Wang B, Sun YG, Zhang GZ, Li YJ, Hou BK*. UGT74D1 is a novel auxin glycosyltransferase from Arabidopsis thaliana. PLoS ONE, 2013, 8(4): e61705. 17. Sun YG, Wang B, Jin SH, Qu XX, Li YJ, Hou BK*. Ectopic Expression of Arabidopsis Glycosyltransferase UGT85A5 Enhances Salt Stress Tolerance in Tobacco. PLoS ONE, 2013, 8(3): e59924. 18. Jin SH, Ma XM, Kojima M, Sakakibara H, Wang YW, Hou BK*. Overexpression of glucosyltransferase UGT85A1 influences trans-zeatin homeostasis and trans-zeatin responses likely through O-glucosylation. Planta, 2013, 237:991-999 19. Li P, Li YJ, Wang B, Yu HM, Li Q, Hou BK*. The Arabidopsis UGT87A2, a stress-inducible family 1 glycosyltransferase, is involved in the plant adaptation to abiotic stresses. Physiologia Plantarum, 2017, 159: 416-432. 20. Wang J, Ma XM, Kojima M, Sakakibara H, Hou BK*. Glucosyltransferase UGT76C1 finely modulates cytokinin responses via cytokinin N-glucosylation in Arabidopsis thaliana. Plant Physiology and Biochemistry. 2013, 65: 9-16 21. Huang XX,Zhao SM,Zhang YY, Li YJ, Shen HN, Li X, Hou BK* (2021) A novel UDP-glycosyltransferase 91C1 confers specific herbicide resistance through detoxification reaction in Arabidopsis. Plant Physiol Biochem, 159: 226-233 22. Zhang GZ, Jin SH, Li P, Jiang XY, Li YJ, Hou BK*. Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis. Plant Cell Reports, 2017, 36:1995-2006. 23. Li Q, Yu HM, Meng XF, Lin JS, Li YJ, Hou BK*. Ectopic expression of glycosyltransferase UGT76E11 increases flavonoid accumulation and enhances abiotic stress tolerance in Arabidopsis. Plant Biology, 2018, 20:10-19 24. Chen L, Wang WS, Liu Q, Dong RR, Li YJ, Chen TT, Hou BK. Overexpression of the UGT76E12 gene modulates seed germination, growth, and response to NaCl, mannitol, and abscisic acid. Biologia Plantarum, 2019, 63: 328-334 25. Liu Q, Zhang YY, Chen L, Chen TT, Li YJ, Hou BK* OsSGT1 is a glucosyltransferase gene involved in the glucose conjugation of phenolics in rice. Plant Molecular Biology Reporter, 2019, 37:41–49 26. Li P, Lei K, Li YJ, He X, Wang S, Liu R, Ji LS*, Hou BK*. Identification and characterization of the first cytokinin glycosyltransferase from rice. Rice, 2019, 12:19 27. Liu Q#, Chen TT#, Xiao DW, Zhao SM, Lin JS, Wang T, Li YJ, Hou BK OsIAGT1 is a glucosyltransferase gene involved in the glucose conjugation of auxins in rice. Rice, 2019, 12:92 https://doi.org/10.1186/s12284-019-0357-z 28. Chen L, Huang XX, Li YJ, Hou BK*. Glycosyltransferase UGT76F1 is involved in the temperature-mediated petiole elongation and the BR-mediated hypocotyl growth in Arabidopsis. Plant Signaling and Behavior. 2020, 15: 8, e1777377