工作与学习经历 2016.04-至今，山东大学，国家糖工程技术研究中心，依次评聘为研究员、教授 2012.06-2016.04，美国韦恩州立大学，化学系，博士后，合作导师：郭忠武教授 2006.09-2012.06，山东大学，药学院，医学硕士、医学博士，导师：娄红祥教授 2001.09-2006.06，泰山医学院（现山东第一医科大学），药学院，医学学士

针对强耐药性细菌感染开展新型糖疫苗研究 围绕能源、环境和生命健康等领域开展新型功能材料研究 生物活性分子全合成及合成方法学研究

1. Xiaoyu Yang, Han Zhang, Qingpeng Zhao, Qingjiang Li, Tiehai Li, Jian Gao.* Total synthesis of the repeating units of highly functionalized O-antigens of Pseudomonas aeruginosa ATCC 27577, O10, and O19. JACS Au, 2024, 4, 2351-2362. 2. Qingpeng Zhao, Shihao Zhou, Yue Wang, Xiaoyu Yang, Youhui Meng, Yanxin Zhang, Jian Gao.* Stereoselective synthesis of the 3,6-branched Fuzi a-glucans up to 15-mer via a one-pot and convergent glycosylation strategy. Chinese Chemical Letters. 2023, 34, 107982. 3. Han Zhang, Aoxin Guo, Youhui Meng, Yue Wang, Jian Gao,* and Xue-Wei Liu.* Stereodirecting effects of 4-O-ortho-cyanobenzyl ether on chemical glycosylation with glucopyranosyl donor. Chinese Journal of Chemistry. 2023, 41, 651-656. 4. Han Zhang, Xiaohan Wang, Youhui Meng, Xiaoyu Yang, Qingpeng Zhao, Jian Gao.* Total synthesis of the tetrasaccharide haptens of Vibrio vulnificus MO6-24 and BO62316 and immunological evaluation of their protein conjugates. JACS Au, 2022, 2, 97-108. 5. Yanxin Zhang, Han Zhang, Ying Zhao, Zhongwu Guo, Jian Gao.* Efficient strategy for α-selective glycosidation of D-glucosamine and its application to the synthesis of a bacterial capsular polysaccharide repeating unit containing multiple α-linked GlcNAc residues. Organic Letters, 2020, 22, 1520-1524. 6. Qingpeng Zhao, Han Zhang, Yanxin Zhang, Shihao Zhou, Jian Gao.* Stereoselective synthesis of a branched α-decaglucan. Organic & Biomolecular Chemistry, 2020, 18, 6549-6557. 7. Han Zhang, Liming Shao, Xiaohan Wang, Yanxin Zhang, Zhongwu Guo,* Jian Gao.* One-pot synthesis of the repeating unit of type VII group B Streptococcus polysaccharide and the dimer. Organic Letters, 2019, 21, 2374-2377. 8. Yanxin Zhang, Shihao Zhou, Xiaohan Wang, Han Zhang, Zhongwu Guo,* Jian Gao.* A new method for α-specific glucosylation and its application to the one-pot synthesis of a branched α-glucan. Organic Chemistry Frontiers, 2019, 6, 762-772. 9. Han Zhang, Shihao Zhou, Ying Zhao, Jian Gao.* Chemical synthesis of the dimeric repeating unit of type Ia group B Streptococcus capsular polysaccharide. Organic & Biomolecular Chemistry, 2019, 17, 5839-5848. 10. Liming Shao, Han Zhang, Yaoyao Li, Guofeng Gu, Feng Cai, Zhongwu Guo,* Jian Gao.* Chemical synthesis of the repeating unit of type II group B Streptococcus capsular polysaccharide. The Journal of Organic Chemistry, 2018, 83, 5920-5930. 11. Jian Gao, Zhongwu Guo. Progress in the synthesis and biological evaluation of lipid A and its derivatives. Medicinal Research Reviews, 2018, 38, 556-601. 12. Jian Gao, Zhifang Zhou, Jiatong Guo, Zhongwu Guo. Synthesis of biotin-labelled core glycans of GPI anchors and their application in the study of GPI interaction with pore-forming bacterial toxins. Chemical Communications, 2017, 53, 6227-6230. 13. Jian Gao, Zhongwu Guo. Synthetic studies of GPI-anchored peptides, glycopeptides, and proteins. RSC Chemical Biology of Glycoproteins, Editor: Zhongping Tan, Lai-Xi Wang. 2017, 253-281. 14. Jian Gao, Zhongwu Guo. Chemical synthesis of the repeating unit of type V group B Streptococcus capsular polysaccharide. Organic Letters, 2016, 18, 5552-5555. 15. Lili Lu,# Jian Gao,# Zhongwu Guo. Labeling cell surface GPIs and GPI-anchored proteins through cell metabolic engineering with artificial inositol derivatives. Angewandte Chemie International Edition, 2015, 54, 9679-9682. 16. Jian Gao, Guochao Liao, Lizhen Wang, Zhongwu Guo. Synthesis of a miniature lipoarabinomannan. Organic Letters, 2014, 16, 988-991. 17. Xin Zan,# Jian Gao,# Guofeng Gu, Shanshan Liu, Bin Sun, Lei Liu, Hong-Xiang Lou. Synthesis and cytotoxic effect of pseudodiosgenyl saponins with thio-ring F. Bioorganic & Medicinal Chemistry Letters, 2014, 24, 1600-1604. 18. Jian Gao, Zhongwu Guo. Synthesis of a tristearoyl lipomannan via preactivation-based iterative glycosylation. The Journal of Organic Chemistry, 2013, 78, 12717-12725. 19. Jian Gao, Zhongwu Guo. Recent progress in the synthesis of GPIs and GPI-anchored proteins. SCIENTIA SINICA Chimica. 2013, 43, 964-983. 20. Jian Gao, Xia Li, Guofeng Gu, Shanshan Liu, Min Cui, Hong-Xiang Lou. Facile synthesis of triterpenoid saponins bearing β-Glu/Gal-(1→3)-β-GluA methyl ester and their cytotoxic activities. Bioorganic & Medicinal Chemistry Letters, 2012, 22, 2396-2400. 21. Jian Gao, Xia Li, Guofeng Gu, Bin Sun, Min Cui, Mei Ji, Hong-Xiang Lou. Efficient synthesis of trisaccharide saponins and their tumor cell killing effects through oncotic necrosis. Bioorganic & Medicinal Chemistry Letters, 2011, 21, 622-627. 22. Yanyan Wang,# Jian Gao,# Guofeng Gu, Gang Li, Changzhi Cui, Bin Sun, Hong-Xiang Lou. In situ RBL receptor visualization and its mediated anticancer activity for solasodine rhamnosides. ChemBioChem. 2011, 12, 2418-2420. 23. Jian Gao, Xia Li, Beibei Lv, Bin Sun, Changjun Zhu, Hong-Xiang Lou. LC-DAD/MS/MS detection of macrocyclic bisbibenzyls from the liverwort Reboulia hemisphaerica and the cell-based screening of their microtubule inhibitory effects. Chinese Journal of Natural Medicines, 2009, 7, 123-128. 下一篇：秦玉琪