范培红 照片

范培红

教授

所属大学: 山东大学

所属学院: 药学院

邮箱:
fanpeihong@sdu.edu.cn

个人主页:
https://www.pharm.sdu.edu.cn/info/1058/4147.htm

个人简介

1996年09月~2000年07月:山东大学药学院,获学士学位; 2000年09月~2003年07月:山东大学药学院,获医学硕士学位; 2006年09月~2009年07月:瑞士日内瓦大学理学院,获博士学位; 2007年03月~2009年10月:瑞士日内瓦大学助教 2013年11月~2017年5月:山东大学基础医学院博士后研究 2003年07月~至今:山东大学药学院

研究领域

活性天然产物研究:主要进行生物活性筛选指导下,天然来源的活性化合物的发现、分离、鉴定及其生物活性研究。 中药药效物质研究:主要研究对象为具有传统用药价值的中药,探讨药效物质及其作用机理。 活性天然产物的结构改造及其活性研究:主要开展典型活性天然产物的结构修饰与生物活性研究。

近期论文

1. Shi XJ, Zhang T, Lou HX, Song HN, Li CH,Fan PH*.Anti-cancer effects of honokiol via mitochondrial dysfunction are strongly enhanced by the mitochondria- targeting carrier berberine.Journal of Medicinal Chemistry2020, 63(20): 11786-11800. 2. Ye YQ, Zhang T, Yuan HQ, Li DF, Lou HX, Fan PH*. Mitochondria-targeted lupane triterpenoid derivatives and their selective apoptosis-inducing anticancer mechanisms. Journal of Medicinal Chemistry, 2017, 60, 6353-6363. 3. He QB, Zhang L, Li T, Li CH, Song HN, FanPH*.GenusSapium(Euphorbiaceae): A review on traditional uses, phytochemistry, and pharmacology. Journal of Ethnopharmacology, 2021, 277: 114206 4. LiT, WangSS,Fan PH*, LouHX.New coumarins and monoterpene galloylglycoside from the stem bark ofSapium baccatum.Fitoterapia,2019,134:435-442. 5. WangSS, LuoQ,Fan PH*.Cannabisin F from hemp (Cannabis sativa) seed suppresses lipopolysaccharide-induced inflammatory responses in BV2 microglia as SIRT1 modulator. International Journal of Molecular Sciences,2019,20(3):507. 6. Wang SS, Luo Q, Zhou YF,Fan PH*.CLG from hemp seed inhibits LPS-stimulated neuroinflammation in BV2 microglia by regulating NF-κB and Nrf-2 pathways. ACS Omega, 2019,4, 16517-16523. 7. Zhou YF, Wang SS, Lou HX,Fan PH*. Chemical constituents of hemp (Cannabis sativaL.) seed with potential antineuroinflammatory activity.Phytochemistry Letters , 2018,23:57-61. 8. Zhou YF, Wang SS, Ji JB, Lou HX,Fan PH*. Hemp (Cannabis sativaL.) seed phenylpropionamides composition and effects on memory dysfunction and biomarkers of neuroinflflammation induced by lipopolysaccharide in mice. ACS Omega, 2018, 3, 15988−15995. 9. LuoQ, Yan XL, Bobrovskaya L, Ji M, Yuan HQ, Lou HX,Fan PH*. Anti-neuroinflammatory effects of grossamide from Hemp seed via suppression of TLR-4-mediated NF-κB signaling pathways in lipopolysaccharide-stimulated BV2 microglia cells. Molecular and Cellular Biochemistry, 2017,428(1), 129-137. 10. Yan XL, Tang JJ, Passos C. dos S., Nurisso A., Simões-Pires C. A., Ji M, Lou HX,Fan PH*. Characterization of lignanamides from hemp (Cannabis sativaL.) seed and their antioxidant and acetylcholinesterase inhibitory activities.Journal of Agricultural and Food Chemistry, 2015, 63, 10611-10619.