王勇军
教授 博士生导师
所属大学: 南通大学
所属学院: 神经再生重点实验室
个人主页:
http://nrl.ntu.edu.cn/sjkxx/xsdw/content/d2fe51c7-d6d6-49be-8080-b71b09465fd7.html
个人简介
王勇军,教授,博士生导师。江苏省神经科学学会副理事长兼秘书长。中国解剖学会再生医学专业委员会委员;中国生理学会转化神经专业委员会委员;江苏省“333”工程培养对象,江苏省“六大人才高峰”资助对象。主要研究方向为组织与器官再生的分子调控及系统演变。 主持承担国家重点研发计划课题(2018YFC1105603),主持完成国家自然科学基金5项等。在NatureCommunications,NucleicAcidsRes,JBiolChem,FASEBJ等期刊发表SCI论文50余篇。研究成果获两项教育部自然科学二等奖。E-mail:wyjbs@ntu.edu.cn。
研究领域
以大鼠中枢和周围神经损伤为实验模型,研究炎症因子对损伤神经中胶质细胞的影响及其分子机制;以低等脊椎动物为动物模型,研究自发性脊髓再生过程中炎症因子的功能转换及其对中枢神经再生的影响,从免疫学角度阐述免疫相关因子和中枢神经再生之间的关系。 代表性论文:
近期论文
1.YingjieWang,SumeiWei,HonghuaSong,XuejieZhang,WenjuanWang,NanDu,TianchengSong,HaoLiang,XiaojunChen,YongjunWang*.Macrophagemigrationinhibitoryfactorderivedfromspinalcordisinvolvedinactivationofmacrophagesfollowinggeckotailamputation.FASEBJ,2019,33:14798–14810 2.ZhangY,ZhouY,ChenS,HuY,ZhuZ,WangY,DuN,SongT,YangY,GuoA*,WangY*.MacrophagemigrationinhibitoryfactorfacilitatesprostaglandinE2productionofastrocytestotuneinflammatorymilieufollowingspinalcordinjury.JNeuroinflammation.2019,16:85. 3.ZhouY,GuoW,ZhuZ,HuY,WangY,ZhangX,WangW,DuN,SongT,YangK,GuanZ,WangY*,GuoA*.MacrophagemigrationinhibitoryfactorfacilitatesproductionofCCL5inastrocytesfollowingratspinalcordinjury.JNeuroinflammation.2018,15:253. 4.ZhuH,XueC*,YaoM,WangH,ZhangP,QianT,ZhouS,LiS,YuB,WangY*,GuX*.miR-129controlsaxonalregenerationviaregulatinginsulin-likegrowthfactor-1inperipheralnerveinjury.CellDeathDis.2018,9:720. 5.HeJ,SunC,GuZ,YangY,GuM,XueC,XieZ,RenH,WangY,LiuY,LiuM,DingF,LeongKW,GuX.Morphology,migration,andtranscriptomeanalysisofSchwanncellcultureonbutterflywingswithdifferentsurfacearchitectures.ACSNano.2018,12:9660-9668. 6.ZhaoY§,WangY§(Co-first),GongJ,YangL,NiuC,NiX,WangY,PengS,GuX,SunC,YangY.Chitosandegradationproductsfacilitatesperipheralnerveregenerationbyimprovingmacrophage-constructedmicroenvironments.Biomaterials,2017,134:64-77. 7.LiuY*,ZhouQ*,WangY*(Co-first),LuoL*,YangJ*,YangL*,LiuM,LiY,QianT,ZhengY,LiM,LiJ,GuY,HanZ,XuM,WangY,ZhuC,YuB,YangY,DingF,JiangJ,YangH,GuX.Gekkojaponicusgenomerevealsevolutionofadhesivetoepadsandtailregeneration.NatureCommunications.2015,6:10033. 8.SunC,WangM,LiuX,LuoL,LiK,ZhangS,WangY,YangY,DingF,GuX.PCAFImprovesGlucoseHomeostasisbySuppressingtheGluconeogenicActivityofPGC-1α.CellRep.2014,9:2250-2262. 9.DongY,GuY,HuanY,WangY,LiuY,LiuM,DingF,GuX,WangY*.HMGB1doesnotmediatetheinflammatoryresponseinspontaneousspinalcordregeneration:AhintforCNSregeneration.JBiolChem,2013,288:18204–18218. 10.YuB,QianT,WangY,ZhouS,DingG,DingF,GuX.miR-182inhibitsSchwanncellproliferationandmigrationbytargetingFGF9andNTM,respectivelyatanearlystagefollowingsciaticnerveinjury.NucleicAcidsRes.2012,40:10356-10365.