学科方向 疾病机制和新药靶标

病原细菌及免疫

1.Jin Y, Zhang M, Zhu F, Peng Q, Weng Y, Zhao Q, Liu C, Bai F, Cheng Z, Jin S, Wu W. NrtR Regulates the Type III Secretion System Through cAMP/Vfr Pathway in Pseudomonas aeruginosa. (2019) Front Microbiol. 10:85. 2.Song D, Meng J, Cheng J, Fan Z, Chen P, Ruan H, Tu Z, Kang N, Li N, Xu Y, Wang X, Shu F, Mu L, Li T, Ren W, Lin X, Zhu J, Fang X, Amrein MW, Wu W, Yan LT, Lü J, Xia T, Shi Y. Pseudomonas aeruginosa quorum-sensing metabolite induces host immune cell death through cell surface lipid domain dissolution. (2019) Nat Microbiol. 4(1):97-111. 3.Zhang Y, Xia B, Li M, Shi J, Long Y, Jin Y, Bai F, Cheng Z, Jin S, Wu W. HigB Reciprocally Controls Biofilm Formation and the Expression of Type III Secretion System Genes through Influencing the Intracellular c-di-GMP Level in Pseudomonas aeruginosa. (2018) Toxins (Basel). 10(11). 4.Liu C, Pan X, Xia B, Chen F, Jin Y, Bai F, Priebe G, Cheng Z, Jin S, Wu W. Construction of a Protective Vaccine Against Lipopolysaccharide-Heterologous Pseudomonas aeruginosa Strains Based on Expression Profiling of Outer Membrane Proteins During Infection. (2018) Front Immunol. 9:1737. 5.Fan Z, Xu C, Pan X, Dong Y, Ren H, Jin Y, Bai F, Cheng Z, Jin S, Wu W. Mechanisms of RsaL mediated tolerance to ciprofloxacin and carbenicillin in Pseudomonas aeruginosa. (2018) Curr Genet. Jun 27. doi: 10.1007/s00294-018-0863-3. 6.You J, Sun L, Yang X, Pan X, Huang Z, Zhang X, Gong M, Fan Z, Li L, Cui X, Jing Z, Jin S, Rao Z, Wu W, Yang H. Regulatory protein SrpA controls phage infection and core cellular processes in Pseudomonas aeruginosa. (2018) Nat Commun. 9(1):1846. 7.Shi J, Liu Y, Zhang Y, Jin Y, Bai F, Cheng Z, Jin S, Wu W. PA5470 Counteracts Antimicrobial Effect of Azithromycin by Releasing Stalled Ribosome in Pseudomonas aeruginosa. (2018) Antimicrob Agents Chemother. Jan 25;62(2). 8.He C, Zhou Y, Liu F, Liu H, Tan H, Jin S, Wu W, Ge B. Bacterial Nucleotidyl Cyclase Inhibits the Host Innate Immune Response by Suppressing TAK1 Activation. (2017) Infect Immun. Aug 18;85(9). 9.Li K, Yang G, Debru AB, Li P, Zong L, Li P, Xu T, Wu W, Jin S, Bao Q. SuhB Regulates the Motile-Sessile Switch in Pseudomonas aeruginosa through the Gac/Rsm Pathway and c-di-GMP Signaling. (2017) Front Microbiol. 8:1045. 10.Deng X, Li M, Pan X, Zheng R, Liu C, Chen F, Liu X, Cheng Z, Jin S, Wu W. Fis Regulates Type III Secretion System by Influencing the Transcription of exsA in Pseudomonas aeruginosa Strain PA14. (2017) Front Microbiol. 8:669 11.Pan X, Dong Y, Fan Z, Liu C, Xia B, Shi J, Bai F, Jin Y, Cheng Z, Jin S and Wu W. In vivo host environment alters Pseudomonas aeruginosa susceptibility to aminoglycoside antibiotics. (2017) Front. Cell. Infect. Microbiol.14;7:83. 12.Chen F, Chen G, Liu Y, Jin Y, Cheng Z, Liu Y, Yang L, Jin S, Wu W. Pseudomonas aeruginosa oligoribonuclease contributes to tolerance to ciprofloxacin by regulating pyocin biosynthesis. (2017) Antimicrob Agents Chemother. 61(3) 13.Weng Y, Chen F, Liu Y, Zhao Q, Chen R, Pan X, Liu C, Cheng Z, Jin S, Jin Y, Wu W. Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence. (2016) Front Microbiol. 15;7:1999. 14.Li M, Long Y, Liu Y, Liu Y, Chen C, Shi J, Zhang L, Jin Y, Yang L, Bai F, Jin S, Cheng Z, Wu W. HigB of Pseudomonas aeruginosa Enhances Killing of Phagocytes by Up-Regulating the Type III Secretion System in Ciprofloxacin Induced Persister Cells. (2016) Front. Cell. Infect. Microbiol. 6:125. 15.Chen G, Zhao Q, Zhu F, Chen R, Jin Y, Liu C, Pan X, Jin S, Wu W, Cheng Z. Oligoribonuclease is required for the type III secretion system and pathogenesis of Pseudomonas aeruginosa. (2016) Microbiol Res. 188-189:90-6. 16.Tan H, Zhang L, Zhao Q, Chen R, Liu C, Weng Y, Peng Q, Bai F, Cheng Z, Jin S, Wu W, Jin Y. DeaD contributes to Pseudomonas aeruginosa virulence in a mouse acute pneumonia model. (2016) FEMS Microbiol Lett. Oct;363(20). 17.Tan H, Zhang L, Weng Y, Chen R, Zhu F, Jin Y, Cheng Z, Jin S, Wu W. PA3297 Counteracts Antimicrobial Effects of Azithromycin in Pseudomonas aeruginosa. (2016) Front Microbiol.7:317. 18.Chen R, Weng Y, Zhu F, Jin Y, Liu C, Pan X, Xia B, Cheng Z, Jin S, Wu W. Polynucleotide Phosphorylase Regulates Multiple Virulence Factors and the Stabilities of Small RNAs RsmY/Z in Pseudomonas aeruginosa. (2016) Front Microbiol. 2;7:247. 19.Guo Q, Wei Y, Xia B, Jin Y, Liu C, Pan X, Shi J, Zhu F, Li J, Qian L, Liu X, Cheng Z, Jin S, Lin J, Wu W. Identification of a small molecule that simultaneously suppresses virulence and antibiotic resistance of Pseudomonas aeruginosa. (2016) Sci Rep. 6:19141. 20.Jin Y, Jin S, Wu W. Regulation of bacterial gene expression by ribosome stalling and rescuing.(2015) Curr Genet. Nov 26