课程讲授：《生化分析与分子诊断》（本科）；药剂学综合试验（本科）；《学术规范及论文写作指导》（研究生）

招生方向：生物与医药；药物化学

教育经历： (1) 2003.9–2008.7, 北京大学药学院，药剂学, 博士，导师：张强教授 (2) 1999.9–2003.7, 北京大学药学院，药学, 本科

工作经历： (1) 2011.1-至今, 南开大学药学院, 副教授 (2) 2017.10-2018.10, University of California, Los Angeles (UCLA), Department of Molecular & Medical_x005f_x000b_Pharmacology, 访问学者，合作导师：Prof. Hsian-Rong Tseng (3) 2008.7-2010.12, 南开大学药学院，讲师

承担了国家自然科学基金面上项目、国家自然科学金青年项目和天津市自然科学基金等项目，作为学术研究骨干参与了一项科技部国际合作项目和一项863项目。

生化分析与药物递送 (1) 近红外荧光成像体系的设计与应用; (2) 抗肿瘤及抗菌光敏分子及其纳米制剂的应用研究；

1. Xiujie Zhao, Hongjie Zhao, Shuo Wang, Zhiwen Fan, Yan Ma, Yongmei Yin, Wei Wang, Rimo Xi,* and Meng Meng*, A Tumor-Targeting Near-Infrared Heptamethine Cyanine Photosensitizer with Twisted Molecular Structure for Enhanced Imaging-Guided Cancer Phototherapy, J. Am. Chem. Soc. 2021, 143, 20828−20836.

2. Xinmin Yue, Yanqi Qiao, Dening Gu, Rui Qi, Hongjie Zhao, Yongmei Yin, Wei Zhao, Rimo Xi,* and Meng Meng*, DNA-Based pH Nanosensor with Adjustable FRET Responses to Track Lysosomes and pH Fluctuations, Anal. Chem. 2021, 93, 7250−7257.

3. Kai Wang, Ruixiao Zhang, Xinmin Yue, Zheng Zhou, Lihuan Bai, Yue Tong, Bei Wang, Dening Gu, Shuo Wang, Yanqi Qiao, Qian Liu, Xue Xue, Yongmei Yin, Rimo Xi* Meng Meng*, Synthesis of Diboronic Acid-Based Fluorescent Probes for the Sensitive Detection of Glucose in Aqueous Media and Biological Matrices, ACS Sens. 2021, 6, 1543−1551.

4. Yanqi Qiao, Qingqing Xue, Xinmin Yue, Yang Liu, Qian Liu, Xiujie Zhao, Dening Gu, Shuo Wang, Kai Wang, Yongmei Yin, Jing Li, Rimo Xi*, Meng Meng*, A DNA nanoscaffold-based electrochemical assay for sensitive determination of O-GlcNAc transferase (OGT) activity and its application in cell-permeable OGT inhibitors screening, Sensors & Actuators: B. Chemical 334 (2021) 129665.

5. The Adjuvant of α-Galactosylceramide Presented by Gold Nanoparticles Enhances Antitumor Immune Responses of MUC1 Antigen-Based Tumor Vaccines, Yonghui Liu, Zhaoyu Wang, Fan Yu, Mingjing Li, Haomiao Zhu, Kun Wang, Meng Meng*, Wei Zhao*, International Journal of Nanomedicine 2021:16.

6. Shuo Wang, Zengyi Liu, Yue Tong, Yunqian Zhai, Xiujie Zhao, Xinmin Yue, Yanqi Qiao, Yonghui Liu, Yongmei Yin, Rimo Xi, Wei Zhao*, Meng Meng*, Improved cancer phototheranostic efficacy of hydrophobic IR780 via parenteral route by association with tetrahedral nanostructured DNA, Journal of Controlled Release 330 (2021) 483–492.

7. Xiujie Zhao, Zhiwen Fan, Yanqi Qiao, Yun Chen, Shuo Wang, Xinmin Yue, Tangliang Shen, Wenting Liu, Jie Yang, Heqi Gao, Xuelin Zhan, Luqing Shang, Yongmei Yin, Wei Zhao, Dan Ding, Rimo Xi*, Meng Meng*, AIEgens Conjugation Improves the Photothermal Efficacy and Near-Infrared Imaging of Heptamethine Cyanine IR-780, ACS Appl. Mater. Interfaces 2020, 12: 16114–16124.

8. Xiujie Zhao, Yun Chen, Guiyu Niu, Dening Gu, Jianning Wang, Yanmei Cao, Yongmei Yin, Xiaogang Li, Dan Ding, Rimo Xi* and Meng Meng*, Photostable pH-Sensitive Near-Infrared Aggregation-Induced Emission Luminogen for Long-Term Mitochondrial Tracking, ACS Appl. Mater. Interfaces, 2019, 11: 13134–13139.

9. Xinmin Yue, Yanqi Qiao, Dening Gu, Zixuan Wu, Wenhui Zhao, Xiaoyu Li, Yongmei Yin, Wei Zhao, Deming Kong, Rimo Xi*, Meng Meng*, Reliable FRET-ON imaging of telomerase in living cells by a tetrahedral DNA nanoprobe integrated with structure-switchable molecular beacon, Sensors & Actuators: B. Chemical 2020, 312, 127943.

10. Wei Liu, Wenxiu Yu, Xiaogang Li, Xiaoyong Zhao, Yu Zhang, Pei Song, Yongmei Yin, Rimo Xi, Meng Meng*, Pyrophosphate-triggered intermolecular cross-linking of tetraphenylethylene molecules for multianalyte detection, Sensors and Actuators B: Chemical, 2018.8.1, 266:170–177.

11. Li Xiaogang#, Liu Wei#, Yue Xinmin, Song Pei, Yin Yongmei, Meng Meng*, Xi Rimo*, A competitive immunoassay using hapten-modified polydiacetylene vesicles for homogeneous and sensitive detection of sodium benzoate, Sensors and Actuators B: Chemical, 2018, 258: 1060–1065.

12. Xiaogang Li, Meng Meng*, Lei Zheng, Zhihuan Xu, Pei Song, Yongmei Yin, Sergei A. Eremin and Rimo Xi*, Chemiluminescence Immunoassay for S-Adenosylhomocysteine Detection and Its Application in DNA Methyltransferase Activity Evaluation and Inhibitors Screening, Anal. Chem., 2016, 88 (17), pp 8556–8561.

13. Kun Xu, Hao Long, Rongge Xing, Meng Meng*, Rimo Xi*, A sensitive chemiluminescent immunoassay to detect Chromotrope FB (Chr FB) in foods, Talanta, 2017, 164: 341–347.

14. Lei Zheng#, Jing Wang#, Jie Zhang#, Zhaorui Song, Yaqing Dong, Yufen Wang, Zhongsheng Tong, Chuan Deng, Yongmei Yin, Meng Meng*, Rimo Xi, Preparation of polyclonal antibodies for nateglinide (NTG) and development of a sensitive chemiluminescent immunoassay to detect NTG in tablets and serum, Talanta 146 (2016) 483–489.

15. Lei Zheng#, Jing Wang#, Yufen Wang, Zhaorui Song, Yaqing Dong, Yongmei Yin & Sergei A. Eremin, Meng Meng*, Rimo Xi*, A sensitive chemiluminescent immunoassay for point-of-care testing of repaglinide in natural dietary supplements and serum, Anal. Bioanal. Chem., 2015, 407:1973–1980.