个人简介
教育经历
2008–2011美国哈佛大学医学院,MGH麻省总医院,博士后 2002–2007美国杜克大学,免疫学博士 2002–2007美国杜克大学,细胞分子生物学专业 1995–2002南开大学医学院,七年制临床医学本硕连读
工作经历
2011.11-南开大学医学院,副教授
承担课题项目:
1国家自然科学基金青年基金:B细胞骨髓免疫耐受机制-抗原非依赖性IgH和Igkappa的V(D)J基因重排(2013-2015)
2南开大学校内基金特别资助类:Ikaros调控急性T淋巴细胞白血病的功能(2012-2014)
3天津市自然科学基金青年项目:B细胞骨髓免疫耐受机制-receptorediting的分子机制(2013-2016)
4南开大学高等学校博士学科点专项科研基金:B细胞受体编辑的分子机制(2012-2015)
讲授课程
1.本科生医学免疫学
2.硕士生医学免疫学
3.留学生医学免疫学
荣誉和奖励
1.2006-2007DukeConferenceTravelFellowship,DukeUniversity
2.2006BernardAmosResearchAward
3.2006Certificateforprofessionalismandacademicexcellence TheGraduateSchool,DukeUniversity
研究领域
1.髓系发生和白血病的发生机制Molecularmechanismofmyelopoiesisandleukemogenesis
2.髓系白血病的治疗MolecularTherapyofAML
3.血液免疫系统的分化和调控Differentiationofhematopoiesisandimmunesystem
近期论文
1.LiY,LiuY,LiuC,LiuF,DouD,ZhengW,LiuW,LiuF.Roleofanon-canonicalsplicevariantoftheHeliosgeneinthedifferentiationofacutelymphoblasticleukemicTcells.OncologyLetters.2018May;15(5):6957-6966.
2.ZhaoS,LiuW,LiY,LiuP,LiS,DouD,WangY,YangR,XiangR,LiuF.AlternativeSpliceVariantsModulatesDominant-NegativeFunctionofHeliosinT-CellLeukemia.PLoSOne.2016Sep28;11(9):e0163328.doi:10.1371/journal.pone.0163328.
3.LiS,LiuW,LiY,ZhaoS,LiuC,HuM,YueW,LiuY,WangY,YangR,XiangR,LiuF.ContributionofsecondaryIgkapparearrangementtoprimaryimmunoglobulinrepertoirediversification.MolecularImmunology.2016Sep22;78:193-206.doi:10.1016/j.molimm.2016.09.006.
4.CaoS,SuX,ZengB,YanH,HuangY,WangE,YunH,ZhangY,LiuF,LiW,WeiH,CheY,YangR.TheGutEpithelialReceptorLRRC19PromotestheRecruitmentofImmuneCellsandGutInflammation.CellReport.2016Feb2;14(4):695-707.doi:10.1016/j.celrep.2015.12.070.
5.SuX,YanH,HuangY,YunH,ZengB,WangE,LiuY,ZhangY,LiuF,CheY,ZhangZ,YangR.ExpressionofFABP4,adipsinandadiponectininPanethcellsismodulatedbygutLactobacillus.ScienceReport.2015Dec21;5:18588.doi:10.1038/srep18588.
6.SuX,MinS,CaoS,YanH,ZhaoY,LiH,ChaiL,MeiS,YangJ,ZhangY,ZhangZ,LiuF,SunW,CheY,YangR.LRRC19expressedinthekidneyinducesTRAF2/6-mediatedsignalstopreventinfectionbyuropathogenicbacteria.NatureCommun.2014Jul16;5:4434.doi:10.1038/ncomms5434.
7.JiangwenZhang,AudreyFJackson,TakuNaito,MareiDose,JohnSeavitt,FeifeiLiu,ElizabethJHeller,MarikoKashiwagi,ToshimiYoshida,FotiniGounari,HowardTPetrie&KatiaGeorgopoulos.Harnessingofthenucleosome-remodeling-deacetylasecomplexcontrolslymphocytedevelopmentandpreventsleukemogenesis.NatureImmunology.2011Nov.1313(1):86-94(Fourthauthor)
8.PabloGómez-delArco,MarikoKashiwagi,AudreyJackson,TakuNaito,JiangwenZhang,FeifeiLiu,BarbaraKee,MarcVooijs,FreddyRadtke,JuanMiguelRedondoandKatiaGeorgopoulos.AlternativePromoterUsageattheNotch1LocusSupportsLigand-IndependentSignalinginTCellDevelopmentandLeukemogenesis.Immunity.2010Nov;Vol.33(5)p.685–698.(Fourthauthor)
9.MarcoDavila*,FeifeiLiu*,LindsayG.Cowell,AnneE.Lieberman,EmilyHeikamp,AnjaliPatel,GarnettKelsoe.Multiple,conservedcrypticrecombinationsignalsinVHgenesegments:detectionofcleavageproductsonlyinpro-Bcells.JournalofExperimentalMedicine.2007Dec24;Vol.204,p3195-3208.(*co-firstauthor)(sciimpactfactor15.61)