个人简介
教育经历 2003.8-2007.8，美国杜克大学博士 1993.9-2000.7,南开大学临床医学硕士
工作经历 2007.8至今南开大学医学院副教授 2000.7-2003.7南开大学医学院讲师
承担课题项目： 1TLR4在肝癌中的作用,国家自然科学基金
讲授课程 1．人体寄生虫学 2.肿瘤前沿进展
研究领域
1CD8+T细胞抗肿瘤作用机制研究.
近期论文
1.Ifit1ProtectsAgainstLipopolysaccharideandD-galactosamine-InducedFatalHepatitisbyInhibitingActivationoftheJNKPathway. ChangA,ChenY,ShenW,GaoR,ZhouW,YangS,LiuY,LuoY,ChuangTH,SunP,LiuC,XiangR. JInfectDis.2015Nov1;212(9):1509-20.doi:10.1093/infdis/jiv221. 2.Yes-associatedprotein(YAP)increaseschemosensitivityofhepatocellularcarcinomacellsbymodulationofp53. BaiN,ZhangC,LiangN,ZhangZ,ChangA,YinJ,LiZ,LuoN,TanX,LuoN,LuoY,XiangR,LiX,ReisfeldRA,StupackD,LvD,LiuC. CancerBiolTher.2013Jun;14(6):511-20.doi:10.4161/cbt.24345. 3.ATF4isdirectlyrecruitedbyTLR4signalingandpositivelyregulatesTLR4-triggedcytokineproductioninhumanmonocytes. ZhangC,BaiN,ChangA,ZhangZ,YinJ,ShenW,TianY,XiangR,LiuC. CellMolImmunol.2013Jan;10(1):84-94.doi:10.1038/cmi.2012.57.Epub2012Dec17. 4.Fra-1promotesbreastcancerchemosensitivitybydrivingcancerstemcellsfromdormancy. LuD,ChenS,TanX,LiN,LiuC,LiZ,LiuZ,StupackDG,ReisfeldRA,XiangR. CancerRes.2012Jul15;72(14):3451-6.doi:10.1158/0008-5472.CAN-11-2536.Epub2012May14. 5.Activatingtranscriptionfactor4increaseschemotherapeuticsresistanceofhumanhepatocellularcarcinoma. ZhangZ,YinJ,ZhangC,LiangN,BaiN,ChangA,LiuY,LiZ,TanX,LiN,LvD,XiangR,TianY,LiuC. CancerBiolTher.2012Apr;13(6):435-42.doi:10.4161/cbt.19295.Epub2012Apr1. 6.TLR2signalingsubpathwaysregulateTLR9signalingfortheeffectiveinductionofIL-12uponstimulationbyheat-killedBrucellaabortus. ZhangCY,BaiN,ZhangZH,LiangN,DongL,XiangR,LiuCH. CellMolImmunol.2012Jul;9(4):324-33.doi:10.1038/cmi.2012.11.Epub2012May28. 7.SOX2promotestumorigenesisandincreasestheanti-apoptoticpropertyofhumanprostatecancercell. JiaX,LiX,XuY,ZhangS,MouW,LiuY,LiuY,LvD,LiuCH,TanX,XiangR,LiN. JMolCellBiol.2011Aug;3(4):230-8.doi:10.1093/jmcb/mjr002.Epub2011Mar17.