胡耀中 照片

胡耀中

讲师

所属大学: 南开大学

所属学院: 医学院

邮箱:
yzhu@nankai.edu.cn

个人主页:
http://medical.nankai.edu.cn/2018/0917/c6615a107985/page.htm

个人简介

教育经历

2014.09-2018.01比利时布鲁塞尔自由大学,生物工程科学专业,博士学位

2013.09-2017.12天津大学,制药工程专业,博士学位

2010.09-2013.07天津大学,生物化工专业,硕士学位

2005.09-2009.07天津大学,生物工程专业,本科学位

工作经历

2018.7-至今南开大学医学院,讲师

荣誉和奖励

2017年,布鲁塞尔自由大学博士奖学金

2012年,硕士研究生国家奖学金

研究领域

1.小分子抗体药物的研究与开发

2.免疫学及肿瘤的免疫治疗

3.肠道微生物与机体紊乱之间的关系研究

近期论文

HuY,LiuC,MuyldermansS.Nanobody-baseddeliverysystemsfordiagnosisandtargetedtumortherapy.FrontiersinImmunology,2017,8:1442.

HuY,RomãoE,VertommenD,VinckeC,Morales-YánezF,GutiérrezC,LiuC,MuyldermansS.GenerationofNanobodiesagainstSlyDanddevelopmentoftoolstoeliminatethisbacterialcontaminantfromrecombinantproteins.ProteinExpressionandPurification,2017,137:64-76.

HuY,LiuJ,HuangH.RecentagentstargetingHIF-1alphaforcancertherapy.JournalofCellularBiochemistry.2013,114:498-509.

CawezF,DurayE,HuY,VandenameeleJ,RomãoE,VinckeC,GalleniM,MuyldermansS,VandevenneM.CombinatorialdesignofananobodythatspecificallytargetsstructuredRNAs.JournalofMolecularBiology,2018,11:1652-1670.

RomãoE,Morales-YánezF,HuY,CrauwelsM,DePauwP,HassanzadehGG,DevoogdtN,AckaertC,VinckeC,MuyldermansS.Identificationofusefulnanobodiesbyphagedisplayofimmunesingledomainlibrariesderivedfromcamelidheavychainantibodies.CurrentPharmaceuticalDesign,2016,22:6500-6518.

LiM,FanX,LiuJ,HuY,HuangH.Selectionbyphagedisplayofnanobodiesdirectedagainsthypoxiainduciblefactor-1alpha(HIF-1alpha).AppliedBiochemistryandBiotechnology,2015,62:738-745.

HuangH,SongC,YangZ,DongY,HuY,GaoF.IdentificationofthereplicationoriginsfromCyanotheceATCC51142andtheirinteractionswiththeDnaAprotein:frominsilicotoinvitrostudies.FrontiersinMicrobiology,2015,6:1370.

FanX,HuY,HuangH.Nanobodies:Novelbiomedicalvehiclesintargetingtumor.JournalofChemicalandPharmaceuticalResearch,2014,6:458-462.