教育与工作经历

2004年9月-2008年7月，曲阜师范大学，生物工程专业，攻读本科

2008年9月-2013年12月，华中农业大学，动物遗传育种与繁殖专业，直接攻博

2014年6月至今，在南京农业大学动物科技学院任教 承担科研项目

主持国家自然科学基金青年项目1项、江苏省自然科学基金青年基金项目1项、国家科技支撑计划子课题1项、中央高校基本科研业务费专项资金2项。

动物分子遗传育种

动物遗传育种与繁殖

1. Wei Wei#, Wei-Ya Zhang#, Jian-Bo Bai, Hai-Xin Zhang, Yuan-Yuan Zhao, Xin-Yun Li* and Shu-Hong Zhao, The NF-kappaB-modulated microRNAs miR-195 and miR-497 inhibit myoblast proliferation by targeting Igf1r, Insr and cyclin genes, Journal of Cell Science, 2016, 129(1): 39-50.

2. Wei Wei#, Wenxing Sun#, Haiyin Han, Weiwei Chu, Lifan Zhang, Jie Chen, miR-130a regulates differential lipid accumulation between intramuscular and subcutaneous adipose tissues of pigs via suppressing PPARG expression, Gene, 2017, 636:23-29.

3. Wei Wei#, Bojiang Li#, Kaiqing Liu, Aiwen Jiang, Chao Dong, Chao Jia, Jie Chen, Honglin Liu, Wangjun Wu*, Identification of key microRNAs affecting drip loss in porcine longissimus dorsi by RNA-Seq, Gene, 2018, 647: 276-282.

4. Weiwei Chu#, Wei Wei#, Haiyin Han, Ying Gao, Kaiqing Liu, Ye Tian, Zaohang Jiang, Lifan Zhang & Jie Chen*, Muscle-specific downregulation of GR levels inhibits adipogenesis in porcine intramuscular adipocyte tissue, Scientific Reports, 2017, 7(1):510.

5. Hongcheng Liu#, Wei Wei#, Weimin Lin, Wensai Yu, Wu Luo, Yingfang Niu, Lifan Zhang, Jie Chen*. miR-32-5p Regulates Lipid Accumulation in Intramuscular Fat of Erhualian Pigs by Suppressing KLF3, Lipids, 2020, DOI 10.1002/lipd.12294.

6. Yongyan Zhao, Xiangsheng Lin, Kaiqing Liu, Ye Tian, Lifan Zhang, Wei Wei*, Jie Chen. Promoter CpG Methylation Status Affects ADRP Gene Expression Level and Intramuscular Fat Content in Pigs, Italian Journal of Animal Science, 2020,19(1): 783-791

7. Xiangsheng Lin, Mengting Yan, Wensai Yu, Yuchen Ma, Lifan Zhang, Wei Wei*, Jie Chen, Hoxa11 and Hoxa13 facilitate slow-twitch muscle formation in C2C12 cells and indirectly affect the lipid deposition of 3T3-L1 cells. Animal Science Journal. 2021, 92: e13544. https://doi.org/10.1111/asj.13544

8. Jiawen He#, Xiangsheng Lin#, Haoxin Yang, Ye Tian, Yuelei Zhao, Lifan Zhang, Wei Wei*, and Jie Chen, UBXN1 is a strong candidate gene in regulation of pork water-holding capacity, Archives Animal Breeding, 64, 109-118, 2021, https://doi.org/10.5194/aab-64-109-2021

9. S. Yu, M. Xia, M. A. Alsiddig, H. Liu, W. Wei* & J. Chen*, Molecular cloning, alternative splicing and mRNA expression analysis of MAGI1 and its correlation with laying performance in geese, British Poultry Science, 2017, 58(2):158-165.

10. Haiyin Han, Wei Wei, Weiwei Chu, Kaiqing Liu, Ye Tian, Zaohang Jiang, and Jie Chen*, Muscle Conditional Medium Reduces Intramuscular Adipocyte Differentiation and Lipid Accumulation through Regulating Insulin Signaling, International Journal of Molecular Sciences, 2017, 18(8): 1799.

11. Weiwei Chu, Wei Wei, Shigang Yu, Haiyin Han, Xiaoli Shi, Wenxing Sun, Ying Gao, Lifan Zhang, Jie Chen*, C2C12 myotubes inhibit the proliferation and differentiation of 3T3-L1 preadipocytes by reducing the expression of glucocorticoid receptor gene, Biochemical and Biophysical Research Communications, 2016, 472(1):68-74.

12. Mengyuan Xia, Wei Wei, Zaohang Jiang, Dandan He, Zhen Li, Shigang Yu, Qiushi Wang, Honglin Liu and Jie Chen*, A Functional Mutation in KIAA1462 Promoter Decreases Glucocorticoid Receptor Affinity and Affects Egg-Laying Performance in Yangzhou Geese, International Journal of Molecular Sciences, 2018, 19: 1531.

13. Shigang Yu, Wei Wei, Mengyuan Xia, Zaohang Jiang, Dandan He, Zhen Li, Haiyin Han, Weiwei Chu, HongLin Liu, Jie Chen*, Molecular characterization, alternative splicing and expression analysis of ACSF2 and its correlation with egg-laying performance in geese, Animal Genetics, 2016, 47(4):451-462.

14. Haoxin Yang, Jiawen He, Wei Wei, Weiwei Chu, Shigang Yu, Ye Tian, Fengyi Peng, Hongcheng Liu, Zengkai Zhang, Jie Chen*, The c.-360 T>C mutation affects PGAM2 transcription activity and is linked with the water holding capacity of the longissimus lumborum muscle in pigs, Meat Science, 2016, 122:139-144