沙强
讲师
个人简介
2010 年毕业于南京理工大学制药工程专业,获得工学学士学位,随后在南京理工大学 硕博连读,师从魏运洋教授,从事重氮化合物参与的合成应用研究,2016 年获得化学工程 与技术博士学位。2014.09-2015.09 期间,受留学基金委全额资助赴美国马里兰大学帕克分校 及德克萨斯大学圣安东尼奥分校访问交流一年,师从 Michael P. Doyle 教授,从事多羰基化 合物用于新颖杂环化合物的合成研究。2016 年 7 月进入南京农业大学理学院工作,目前已 以第一作者身份在Organic Letters, Chemical Communications, The Journal of Organic Chemistry, Advanced Synthesis & Catalysis, ChemCatChem 等知名期刊发表十多篇 SCI 论文。此外参与了 教材《药物合成反应简明教程》5.4 节的编写,发表英文综述一章。
研究领域
催化不对称合成、杂环骨架构建、卡宾化学、生物活性分子设计
近期论文
1. Qiang Sha*#, Haixuan Liu#, Yuan Li. Trifluoroacetic Acid Catalyzed Cascade Reactions of 2,3- Diketoesters with Cyclohexane-1,3-diones: Strategy Towards 4- Hydroxybenzofuran Derivatives. Advanced Synthesis & Catalysis, 2019, doi: 10.1002/adsc.201900056. 2. Qiang Sha*, Junke Wang, and Michael P. Doyle. Synthesis of 1H-Pyrrol-3(2H)-ones via Three Component Reactions of 2,3-Diketo Esters, Amines, and Ketones. The Journal of Organic Chemistry, 2018, 83(18), 11288-11297. 3. Yang Yu, Qiang Sha, Hui Cui, Kory S. Chandler, and Michael P. Doyle*. Displacement of Dinitrogen by Oxygen: A Methodology for the Catalytic Conversion of Diazocarbonyl Compounds to Ketocarbonyl Compounds by 2,6-Dichloropyridine-N-oxide. Organic Letters, 2018, 20 (3), 776-779. 4. Kai Luo, Ling Zhang, Jing Ma, Qiang Sha, and Lei Wu*. Acetic Acid Mediated Sulfonylation of Allenylphosphine Oxides: Divergent Synthesis of Bifunctionalized 1,3-Butadienes and Allenes. The Journal of Organic Chemistry, 2017, 82(13), 6978-6985. 5. Qiang Sha, Hadi Arman, Michael P. Doyle*. Asymmetric Synthesis of 1H-Pyrrol-3(2H)-ones from 2,3-Diketoesters by Combination of Aldol Condensation with Benzilic Acid Rearrangement. Chemical Communications, 2016, 52,108-111. 6. Qiang Sha, Hadi Arman, Michael P. Doyle*. Three-Component Cascade Reactions with 2,3 Diketoesters: A Novel Metal-Free Synthesis of 5-Vinyl-pyrrole and 4-Hydroxy-indole Derivatives. Organic Letters, 2015, 17, 3876-3879. 7. Qiang Sha, Yunyang Wei*. Copper(I)-Catalyzed Wittig Olefination Reactions of N Tosylhydrazones with Trifluoromethylketones. ChemCatChem, 2014, 6, 131-134. 8. Qiang Sha, Yunyang Wei*. One-pot Multistep Synthesis of Trisubstituted Alkenes from N Tosylhydrazones and Alcohols. Synthesis, 2014, 46, 2353-2361. 9. Qiang Sha, Haixuan Liu, Yunyang Wei*. Design and Synthesis of 3-Trifluoromethyl-3H pyrazoles and Further Investigations of Their Transformation into Novel 1H-Pyrazoles. European Journal of Organic Chemistry, 2014, 34, 7707-7715. (Qiang Sha and Haixuan Liu contributed equally) 10. Qiang Sha, Yunyang Wei*. An Efficient One-Pot Synthesis of 3, 5-Diaryl-4-bromopyrazoles by 1,3-Dipolar Cycloaddition of In Situ Generated Diazo Compounds and 1-Bromoalk-1-ynes. Synthesis, 2013, 45, 413-420. (Highlighted by Organic Chemistry Portal) 11. Qiang Sha, Yunyang Wei*. Base and Solvent Mediated Decomposition of Tosylhydrazones: Highly Selective Synthesis of N-Alkyl Substituted Hydrazones, Dialkylidenehydrazines, and Oximes. Tetrahedron, 2013, 69, 3829-3835. 12. Qiang Sha, Yunyang Wei*. One-Pot Synthesis of S-Alkyl Dithiocarbamates via The Reaction of N-Tosylhydrazones, Carbon Disulfide and Amines. Organic & Biomolecular Chemistry, 2013, 11, 5615-5620. 13. Qiang Sha, Yifei Ling, Wenyong Wang, Yunyang Wei*. Capture of In Situ Generated Diazo Compounds or Copper Carbenoids by Triphenylphosphine: Selective Synthesis of trans Alkenes and Unsymmetric Azines via Reaction of Aldehydes with Ketone-Derived NTosylhydrazones. Advanced Synthesis & Catalysis, 2013, 355, 2145-2150. 发表综述或章节 1. Qiang Sha, Yongming Deng, Michael P. Doyle*. The Future of Catalysis by Chiral Lewis Acids. Topics in Organometallic Chemistry, 2015, doi: 10.1007/3418_2015_141. 2. 参与教材《药物合成反应简明教程》5.4 节(310-335 页)的编写。《药物合成反应简明 教程》,2013 年,科学出版社(978-7-03-038164-4),魏运洋、罗军、张树鹏主编。