胡玉静
副教授 硕导
所属大学: 南京工业大学
所属学院: 生物与制药工程学院
个人简介
胡玉静,生物与制药工程学院副教授,硕士生导师。博士毕业于浙江大学,期间于英国女王大学交流学习。主要研究方向:(1)氧化还原酶催化转化及其蛋白质工程;(2)连续流中多酶催化转化合成高价值产品。以第一作者或通讯作者身份(含共同)在Angewandte Chemie International Edition、Chemical Engineering Journal、ACS Macro Letters、Advanced Synthesis & Catalysis、Chemical Communications等刊物发表多篇论文,授权中国发明专利8项。主持国家自然科学基金青年基金等数项省部级及国家级项目,以及企业委托项目3项,并获批中国石化2023(首届)“种子计划”课题。
研究领域
(1)氧化还原酶催化转化及其蛋白质工程;(2)连续流中多酶催化转化合成高附加值产品
近期论文
Yujing Hu*, et al. Four-Step Continuous-Flow Biosynthesis of A Chiral Precursor for Angiotensin-Converting Enzyme Inhibitors, Chemical Engineering Journal, 2025, 53, 158331. Yujing Hu*, et al. Ene-Reductase-Catalyzed Aromatization of Simple Cyclohexanones to Phenols, Angewandte Chemie International Edition, 2024, 63, e202408359. Yujing Hu, et al. Enantiocomplementary Synthesis of Tetrahydrofurans by Engineered Halohydrin Dehalogenases, Advanced Synthesis & Catalysis, 2024, 366. Yujing Hu*, et al. A Photo-Enzymatic Cascade to Access Dihydrocoumarins from Incompatibility to Compatibility, Molecular Catalysis, 2024, 554, 113852. Yujing Hu, et al. Biocatalysts Used for Multi-Step Reactions in Continuous Flow, Chemical Engineering Journal, 2022, 437, 135400. Yujing Hu*; et al. Photo-mediated spirocyclization of N-benzyl propiolamide with N-iodosuccinimide for access to Azaspiro[4.5] deca-6,9-diene-3,8-dione, The Journal of Organic Chemistry, 2022, 87, 8445−8457. Yujing Hu, et al. The Mutagenesis of A Single Site for Enhancing or Reversing the Enantio- or Regiopreference of Cyclohexanone Monooxygenases, Chemical Communications, 2020, 56(65), 9356-9359. Yujing Hu, et al. Dual-Enzyme-Catalyzed Synthesis of Enantiocomplementary Polyesters, ACS Macro Letters, 2019, 8(11), 1432-1436. Yujing Hu, et al. ‘‘Top’’ or ‘‘Bottom’’ Switches of A Cyclohexanone Monooxygenase Controlling the Enantioselectivity of the Sandwiched Substrate, Chemical Communications, 2019, 55(15), 2198-2201. Yujing Hu, et al. Customizing the Enantioselectivity of A Cyclohexanone Monooxygenase by A Strategy Combining “Size-Probes” With in Silico Study, ChemCatChem, 2019, 11(20), 5085-5092.