张继虹教授、博士、硕士生导师 云南省中青年学术和技术带头人后备人才，昆明市中青年学术和技术带头人后备人选；云南省医师协会药物临床评价与研究专业委员会委员、常委、副主任委员，《美国肿瘤治疗和药理》杂志编委。1992. 09 -- 1996.07沈阳药科大学，药学系，获理学学士学位； 2007.01 -- 2010.03英国诺丁汉大学药学院，获药学博士学位 1996. 07-- 2004. 05云南省第一人民医院药剂科，主管药师； 2001.01 -- 2001.06中山医科大学临床药理基地进修药代与药动学 2004. 06 -- 2005.06英国诺丁汉大学药学院，访问学者； 2005.09 -- 2006.09英国诺丁汉大学药学院药物分析中心，助理研究员； 2007.01 -- 2010.01英国Pharminox Ltd药理学科研人员； 2010.04 --至今昆明理工大学医学院，教授

主要为抗肿瘤药物的筛选及药理机制的研究

1. Yang Z, Wei D, Liu F, Liu J, Wu X, Stevens MFG, Bradshaw TD, Luo Y, Zhang J. Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells. J Cell Biochem. 2018 Jan 13. doi: 10.1002/jcb.26674. 2. Xiaoli Dai, Jing Liu, Yin Nian, Ming-HuaQiu, Ying Luo, Jihong Zhang*.A novel cycloartanetriterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells.Oncol Rep.2017 Apr;37(4):2079-2086. doi: 10.3892/or.2017.5444. Epub 2017 Feb 14. IF 2.49 3. Jing Liu, Tongyang Liu, HancunMou, Chao Huang, Shengjiao Yan, Jun Lin, Ying Luo and Jihong Zhang. An Isoquinolin-1(2H)-Imine Derivative Induces Cell Death via Generation of Reactive Oxygen Species and Activation of JNK in Human A549 Cancer Cells. Journal of Cellular Biochemistry. 4. Fu-Chao Yu, Xin-Rong Lin, Zhi-Cheng Liu, Ji-Hong Zhang,*Fei-Fei Liu, Wei Wu, Yu-Lu Ma, Wen-Wen Qu, Sheng-Jiao Yan,* and Jun Lin*Beyond the Antagonism: Self-Labeled Xanthone Inhibitors as Modeled “Two-in-One” Drugs in Cancer Therapy. ACS Omega 2017, 2, 873？889. DOI: 10.1021/acsomega.6b00545 5. YafeiGuo, Yushun Zhang, Jiuling Li, Fen Zhao, Yang Liu, Min Su, Yubo Jiang, Yuqi Liu,Jihong Zhang,* Bo Yang,* and Rui Yang*Inclusion Complex of Podophyllotoxin with γ-Cyclodextrin: Preparation, Characterization, Anticancer Activity, Water-Solubility and Toxicity Chin. J. Chem. 2016, 34, 425—431 6. YufengRen, Ying Liu, RaomeiNiu, XialiLiao ,Jihong Zhang*, Bo Yang. Host-guest inclusion system of oleanolic acid with methyl-b- cyclodextrin: Preparation, characterization and anticancer activity.Journal of Molecular Structure 1117 (2016) 1-7. 7. YufengRen, Ying Liu, Zhikuan Yang, RaomeiNiu, Kai Gao, Bo Yang, Xiali Liao, Jihong Zhang. Solid Inclusion Complexes of Oleanolic Acid with Amino-appended β- Cyclodextrins (ACDs): Preparation, Characterization, Water Solubility and Anticancer Activity. Materials Science & Engineering C[J], 2016, 05(022) 8. Zhu M, Liu T, Zhang J, Jia S, Tang W, Luo Y. Association between rs1344706 of ZNF804A and schizophrenia: a meta-analysisGenomics Proteomics Bioinformatics. 2014 Dec;12(6):292-6 9. Jing Liu, Wenhui Huang, Ruoyu Zhou, ShutingJia, Wenru Tang, Ying Luo, and Jihong Zhang*. Bisphosphonates in the Treatment of Patients With Metastatic Breast, Lung, and Prostate Cancer.Medicine，Volume 94, Number 46, November 2015.1-5. 10. Liu J, Tang W, Sang L, Dai X, Wei D, Luo Y, Zhang J. Milk, Yogurt, and Lactose Intake and Ovarian Cancer Risk: A Meta-Analysis.Nutr Cancer. 2015; 67(1):68-72 11. Yin Nian，Jing Yang，Tong-Yang Liu，Ying Luo，Ji-Hong Zhang*, Ming-HuaQiu. New Anti-angiogenic Leading StructureDiscovered in the Fruit of Cimicifugayunnanensis. Scientific Reports 2015，5:9026,1-7. 12. Haiyu Yang, Danping Wei,Kunxian Yang,WenruTang,YingLuo,Jihong Zhang*. The Prognosis of MGMT Promoter Methylation in Glioblastoma Patients of Different Race: A Meta-analysis. Neuroche Res 2014，39：2277-2287. 13. Jihong Zhang, Marc Hummersone, Charles S Matthews, Malcolm FG Stevensand Tracey D Bradshaw. N3-Substituted temozolomide analogs overcome methylguanine DNA methyltransferase and mismatch repair precipitating apoptotic and autophagic cancer cell death.Oncology2015;88:28–48 14. Ai Zhipeng, NingXianming, Shou Tao, Tang wenru andZhang Jihong*. Association of interleukin-6 promoter polymorphism with knee osteoarthritis: a meta-analysis.Chin Med J2014;127(13) 15. Rui Yang, Jing-Bo Chen, Chuan-Fan Xiao, Zhi-Cheng Liu, Zhan-Yong Gao,Sheng-Jiao Yan,Ji-Hong Zhang*, Hong-Bin Zhang, Jun Lin. Inclusion complex of GA-13316 withβ-cyclodextrin: Preparation, characterization, molecular modeling, and in vitro evaluation.Carbohydrate Polymers, 2014, 111655–662. 16. Lei Feng，Shi-yanNian，Jihongzhang*.The GG genotype oftelomerase reverse transcriptase at genetic locus rs2736100 is associated with human atherosclerosis risk in the Han Chinese population. PloS One, 2014, 9(1), 85719. 17. Yi-Chuan Zhang, Zhi-Cheng Liu, Rui Yang,Ji-Hong Zhang, Sheng-Jiao Yan and Jun Lin.Regioselective construction of 1,3-diazaheterocycle fused [1,2-a] [1,8] naphthyridine derivatives via cascade reaction of quinolines with heterocyclic ketene aminals: a joint experimental–computational approach.Org. Biomol. Chem., 2013, 11, 7276–7288 18. Liang Xi, Jian-Qiang Zhang,Zhi-Cheng Liu,Ji-Hong Zhang, Ju-Fang Yan,Yi Jin，Jun Lin. Novel 5-anilinoquinazoline-8-nitro derivatives as inhibitors of VEGFR-2 tyrosine kinase: synthesis, biological evaluation and molecular docking.Org. Biomol. Chem., 2013,11, 4367-4378 19. Sheng-Jiao Yan, Ying Dong, QiongPeng, Yin-Xin Fan,Ji-Hong Zhang*, Jun Lin. Synthesis of polyhalo 2-aryl-4-aminoquinazoline and 3-amino-indazoles as anticancer agents.RSC Advances.2013, 3, 5563-5569 20. Bo Yang, Yu-Lin Zhao, Xia Yang, Xia-Li Liao, Jian Yang,Ji-Hong Zhang,Chuan-Zhu Gao. Scutellarin-cyclodextrin conjugates: Synthesis, characterization and anticancer activity.Carbohydrate Polymers.2013, 92, 1308– 1314