个人简介
教育及工作经历 2002.9-2006.7 博士研究生(获理学博士学位),导师:宿兵研究员 中国科学院昆明动物研究所遗传资源与进化国家重点实验室, 中国科学院昆明灵长类研究中心。 1999.9-2002.7 硕士研究生(获理学硕士学位),导师:肖春杰教授 云南大学人类遗传学研究中心 1992.9-1996.7本科(获农学学士学位) 西南农业大学(西南大学) 研究工作经历: 2015.1-至今,教授。 昆明理工大学灵长类转化医学研究中心。灵长类的基因组多样性与临床前个体化医疗研究方向负责人。 2009.9—2014.12,副研究员。中国科学院大学硕士导师。 中国科学院昆明动物研究所遗传资源与进化国家重点实验室。 2006.8-2009.8,助理研究员。 中国科学院昆明动物研究所遗传资源与进化国家重点实验室。
研究领域
现从事灵长类基因组多样性研究,主要方向为人群环境适应性进化研究,疾病发病的遗传基础研究,灵长类个性化医疗研究。
近期论文
1. Yang ZH, Zhong H, Chen J, Zhang XM, Zhang H, Luo X, Xu SH, Chen H, Lu DS, HanYL, Li JK, Fu LJ, Qi XB, Peng Y, Xiang K, Lin Q, Guo Y, Li M, Cao XY, Zhang YF, Liao SY, Peng YM, Zhang L, Guo XS, Dong SS, Liang F, Wang J, Willden A, Seang Aun H, Serey B, Sovannary T, Bunnath L, Samnom H, Mardon G, Li QW, Meng AM *, Shi H * (共同通讯作者)& Su B *. A genetic mechanism for convergent skin lightening during recent human evolution. Mol Bio Evol. 2016 May 33(5):1177–1187.(IF:13.649) 2. Zhang XM, Liao SY, Qi XB, Liu JW, Kampuansai J, Zhang H, Yang ZH, Serey B, Sovannary T, Bunnath L, Seang Aun H, Samnom H, Kangwanpong D, Shi H*(共同通讯作者) & Su B. Y-chromosome diversity suggests southern origin and Paleolithic backwave migration of Austro-Asiatic speakers from eastern Asia to the Indian subcontinent. Sci. Rep. 2015 Oct, 5: 15486; doi: 10.1038/srep15486. 3. Zhang XM, Kampuansai J, Qi XB, Yan S, Yang ZH, Serey B, Sovannary T, Bunnath L, Seang Aun H, Samnom, Kutanan W, Luo X, Liao SY, Kangwanpong D, Jin L, Shi H*(共同通讯作者)and Su B*.An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs. PLoS ONE. 2014 June, 9(6):e101020. 4. Kraaijenbrink T, van der Gaag KJ, Zuniga SB, Xue Y, Carvalho-Silva DR, Tyler-Smith C, Jobling M A, Parkin EJ, Su B, Shi H, Xiao CJ, Tang WR, Kashyap VK, Trivedi R, Sitalaximi T, Banerjee J, Tshering of Gasel? K, Tuladhar NM, Opgenort JRML, van Driem GL, Barbujani G, Peter de Knijff. A Linguistically Informed Autosomal STR Survey of Human Populations Residing in the Greater Himalayan Region. PLoS ONE. 2014 March 9(3): e91534. 5. Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, N?then MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Arias Vasquez A, Hibar DP, Franke B, Martin NG, Wright MJ; MooDS Bipolar Consortium; Swedish Bipolar Study Group; Alzheimer’s Disease Neuroimaging Initiative; ENIGMA Consortium; CHARGE Consortium, Su B. Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Mol Psychiatry. 2014 Apr;19(4):452-61. (IF 15.147) 6. Zhang XM, Qi XB, Yang ZH, Serey B, Sovannary T, Bunnath L, Seang Aun H, Samnom, Zhang H, Lin Q, van Oven M, Shi H *(共同通讯作者) and Su B. Analysis of Mitochondrial Genome Diversity Identifies Novel and Ancient Maternal Lineages in Cambodian Aborigines. Nature Communications. 2013, 4:2599.(IF 10.742) 7. Qi XB, Cui CY, Peng Y, Zhang XM, Yang ZH, Zhong H, Zhang H, Xiang K, Cao XY, Wang Y, Ouzhuluobu, Basang, Ciwangsangbu, Bianba, Gonggalanzi, Wu TY, Chen H, Shi H*(共同通讯作者)and Su B. Genetic evidence of Paleolithic colonization and Neolithic expansion of modern humans on the Tibetan Plateau. Mol Biol Evol. 2013, 30(8):1761-1778. (IF 14.308) 8. Shi H, Qi XB, Zhong H, Peng Y, Zhang XM, Ma RLZ and Su B. Genetic evidence of an East Asian origin and Paleolithic northward migration of Y-chromosome haplogroup N. PLoS ONE. 2013 June,8(6):e66102. 9. Xiang K, Ouzhuluobu, Peng Y, Yang ZH, Zhang XM, Cui CY, Zhang H, Li M, Zhang YF, Bianba, Gonggalanzi, Basang, Ciwangsangbu, Wu TY, Chen H, Shi H, Qi XB, Su B. Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation. Mol Biol Evol. 2013, 30(8):1889-1898. (IF 14.308) 10. Li M, Luo XJ, Xiao X, Shi L, Liu XY, Yin LD, Ma XY, Yang SY, Pu XF, Yu J, Diao HB, Shi H, and Su B. Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population. The World Journal of Biological Psychiatry, 2011 March, 14(2): 91-99. 11. Li R, Zhang XM, Campana MG, Huang JP, Chang ZH, Qi XB, Shi H, Su B, Zhang RF, Lan XY, Chen H and Lei CZ. Paternal origins of Chinese cattle. Animal Genetics. 2013, 44(4):446-449. 12. Qi XB, Shi H, Cui CY, Bianba, Ouzhuluobu, Wu TY and Su B. Peopleing of the Tibetan Plateau and genetic adaptation to high-altitude hypoxia in Tibetans. Science. 2012 December; 388(6113):1485(12-13). 13. Shi H. A commentary on “A multiplex SNP assay for the dissection of human Y-chromosome haplogroup O representing the major paternal lineage in East and Southeast Asia”. J Hum Genet. 2012, 57:5. 14. Peng Y, Yang ZH, Zhang H, Cui CY, Qi XB, Luo XJ, Tao X, Wu TY, Ouzhuluobu, Basang, Ciwangsangbu, Danzengduojie, Chen H, Shi H*(共同通讯作者)& Su B*. Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas. Mol Biol Evol. 2011, 28:1075-1081. (IF 11.221) 15. Zhong H, Shi H,*(共同第一作者), Qi XB, Duan ZY, Tan PP, Jin L, Su B & Ma RZ. Extended Y-chromosome investigation suggests post-Glacial migrations of modern humans into East Asia via the northern route. Mol Biol Evol. 2011, 28, 717-727.(IF 11.221) 16. Shi H and Su B. Molecular Adaptation of Modern Human Populations. Intern J Evol Bio. 2011, 484769, doi:10.4061/2011/484769. 17. Peng Y, Shi H, Qi XB, Xiao CJ, Zhong H, Ma Z RL, Su B. Genetic evidence of rice culture driven selection on the ADH1B Arg47His polymorphism in East Asian populations. BMC Evolu Biol. 2010, 10:15. 18. Zhong H, Shi H, Xiao CJ, Ma RLZ and Su B. Global Distribution of Y-Chromosome Haplogroup C Reveals the Prehistoric Migration Routes of African Exodus and Early Settlement in East Asia. J Hum Genet. 2010, 55, 428-35. 19. Shou WH, Qiao EF, Wei CY, Dong YL, Tan SJ, Shi H, Tang WR, Xiao CJ. Y-chromosome distributions among populations in Northwest China identify significant contribution from Central Asian pastoralists and lesser influence of western Eurasians. J Hum Genet. 2010, 5:1–9. 20. Shi H, Tan SJ, Zhong H, Hu WW, Levine A, Xiao CJ, Peng Y, Qi XB, Shou WH, Ma Z RL, Li Y, Su B and Lu X. Winter Temperature and UV Are Tightly Linked to Genetic Changes in the p53 Tumor Suppressor Pathway in Eastern Asia. Am J Hum Genet. 2009 April; 84(4), 534–541. (Featured Article)(IF 12.16)