张文科
教授
所属大学: 吉林大学
所属学院: 超分子结构与材料国家重点实验室
个人简介
1973年出生于辽宁盖州。分别于1997和2002年在吉林大学获得本科及博士学位,指导教师是张希教授。2001-2002年在德国慕尼黑大学(LMU)Hermann E. Gaub教授研究组博士生联合培养。2003-2007年于英国诺丁汉大学从事博士后研究。2007年6月加入吉林大学超分子结构与材料国家重点实验室,任教授、博士生导师。2011年入选教育部“新世纪优秀人才支持计划”,2015年获得国家杰出青年基金资助,2018年入选国家科技创新领军人才。
研究领域
单分子力谱与超分子相互作用,聚合物结晶与熔融,病毒组装与解组装,机械化学
近期论文
X. J. Lyu, Y. Song, W. Feng, W. K. Zhang*, Direct observation of single-molecule stick-slip motion in polyamide single crystals, ACS Macro Lett., 2018, 7, 762−766. P. Yang, Y. Song, W. Feng, W. K. Zhang*, Unfolding of a single polymer chain from the single crystal by air-phase single-molecule force spectroscopy: toward better force precision and more accurate description of molecular behaviors, Macromolecules, 2018, 51, 7052−7060. Z. D. Li, Y. Song, A. S. Li, W. Q. Xu, W. K. Zhang*, Direct observation of the wrapping/unwrapping of ssDNA around/from a SWCNT at the single-molecule level: towards tuning the binding mode and strength, Nanoscale, 2018, 10, 18586-18596. W. Feng, Z. G. Wang, W. K. Zhang*, Effect of chain conformation on the single-molecule melting force in polymer single crystals: steered molecular dynamics simulations study, Langmuir, 2017, 33, 1826−1833. H. Zhang, X. Li, Y. J. Lin, F. Gao, Z. Tang, P. F. Su, W. K. Zhang*, Y. Z. Xu, W. G. Weng*, R. Boulatov*, Multi-modal mechanophores based on cinnamate dimers, Nat. Commun., 2017, 8, 1147. X. L. Kou, W. Zhang, W. K. Zhang*, Quantifying the interactions between PEI and double-stranded DNA: toward the understanding of the role of PEI in gene delivery, ACS Appl. Mater. Interfaces 2016, 8, 21055−21062. Y. R. Xue, X. Li, H. B. Li, W. K. Zhang*, Quantifying thiol-gold interactions towards the efficient strength control, Nat. Commun., 2014, 5:4348. N. N. Liu, Y. Chen, B. Peng, Y. Lin, Q. Wang*, Z. H. Su, W. K. Zhang*, H. B. Li, J. C. Shen, Single-molecule force spectroscopy study on the mechanism of RNA disassembly in tobacco mosaic virus, Biophys. J., 2013, 105, 2790-2800. N. N. Liu, B. Peng, Y. Lin, Z. H. Su, Z. W. Niu, Q. Wang, W. K. Zhang*, H. B. Li, J. C. Shen, Pulling genetic RNA out of tobacco mosaic virus using single-molecule force spectroscopy, J. Am. Chem. Soc., 2010, 132, 11036-11038. K. Liu, Y. Song, W. Feng, N. N. Liu, W. K. Zhang*, X. Zhang, Extracting a single polyethylene oxide chain from a single crystal by a combination of atomic force microscopy imaging and single-molecule force spectroscopy: toward the investigation of molecular interactions in their condensed states, J. Am. Chem. Soc., 2011, 133, 3226-3229.