教育经历 1997-2001 吉林大学化学学院 化学基地班 学士 2001-2007 吉林大学化学学院 物理化学专业 博士 工作经历 2007-2010 吉林大学生命科学学院分子酶学工程教育部重点实验室 讲师 2010-2016 吉林大学生命科学学院分子酶学工程教育部重点实验室 副教授 2012-2013 美国乔治城大学化学学院访问学者 2013-2015 美国休斯敦卫理公会研究所纳米医学中心博士后 2016-至今 吉林大学生命科学学院分子酶学工程教育部重点实验室 教授 博士生导师

酶与纳米生物学：1.纳米酶理性设计与催化机制研究；2.机器学习辅助的生物传感器与应用；3.生物活性肽与氧化应激

Huang, Sijun; Yu, Liqiang; Zhang, Kun; Lv, Jiachen; Xiang, Henglong; Zhu, Dongwei; Li, Huan; Zhang, Shuning; Liu, Xinyu; Wang, Ying; Guo, Yi*; Xu, Li*; Tailored protein corona behavior in titanium dioxide nanosheet fluorescence biosensor for protein quantification assays, Journal of Colloid and Interface Science, 2025, 683, 106-115. Huang, Sijun; Xiang, Henglong; Lv, Jiachen; Zhu, Dongwei; Yu, Liqiang; Guo, Yi*; Xu, Li*; Au nanozyme-based colorimetric sensor array integrates machine learning to identify and discriminate monosaccharides, Journal of Colloid and Interface Science, 2024, 672, 200-208. Zhang, Mingming; Zhang, Xi; Huang, Sijun; Cao, Yueming; Guo, Yi*; Xu, Li*; Programmed nanocarrier loaded with paclitaxel and dual-siRNA to reverse chemoresistance by synergistic therapy, International Journal of Biological Macromolecules, 2024, 261, 129726. Huang, Sijun; Xiang, Henglong; Lv, Jiachen; Guo, Yi*; Xu, Li*; Propelling gold nanozymes: catalytic activity and biosensing applications, Analytical and Bioanalytical Chemistry, 2024, 416, 5915–5932. Zhao, Yanping; Geng, Xu; Zhou, Xiaoling; Xu, Li; Li, Shuai; Li, Zhengqiang; Guo, Yi*; Li, Chen*; A novel high-stability bioelectrochemical sensor based on sol-gel immobilization of lactate dehydrogenase and AuNPs-rGO signal enhancement for serum pyruvate detection, Analytica Chimica Acta, 2023, 1265, 341335. Xiang, Henglong; Huang, Sijun; Zhu, Dongwei; Yu, Liqiang; Liu, Rui; Guo, Yi*; Xu, Li*; Au nanozyme driven cascading catalysis in Tollens' reaction: an insight of glucose oxidase-Like mechanism, Chemistry-A European Journal, 2023, 29(34), e202300454. Zhang, Xi; Zhang, Mingming; Huang, Sijun; Ohtani, Kiyoshi; Xu, Li*; Guo, Yi*; Engineered polymeric nanovector for intracellular peptide delivery in antitumor therapy, International Journal of Nanomedicine, 2023, 18, 5343-5363. Li, Zhiguo; Zhang, Shan; Xu, Li; Fang, Xuexun; Wan, Youzhong; Yu, Dahai*; Guo, Yi*; A tetrapeptide from maize combined with probiotics exerted strong anti-inflammatory effects and modulated gut microbiota in DSS-induced colitis mice, Food & Function, 2022, 13(24), 12602-12618. (封面文章)