个人简介
教育经历 1992.9 - 1996.6:武汉大学,本科毕业,获学士学位。 1996.9 - 2002.6:武汉大学,研究生毕业,获理学博士学位。 工作经历 2002.3 - 2015.11:生命科学与技术学院,先后担任讲师、副教授。 2015.11 - 至今:生命科学与技术学院,担任教授,在职。
研究领域
细胞生物学与生物物理学:细胞内的物质运输,特别是膜转运过程的分子机理与调控机制,以及物质运输障碍对细胞内稳环境的影响,如导致免疫相关和神经退行性疾病的发生。
近期论文
[1] Shi X, Duan F, Lin L, Xu Q, Xu T, Zhang R..WIP-1 and DBN-1 promote scission of endocytic vesicles by bridging actin and Dynamin-1 in the C. elegans intesine.J Cell Sci,2019,jsc228023 [2] Wan M, Zhang W, Tian Y, Xu C, Xu T, Liu J, Zhang R.Unraveling a molecular determinant for clathrin-independent internalization and lysosomal targeting of M2 muscarinic acetylcholine receptor.Sci Rep,2015,11408 [3] Chen S, Li L, Li J, Liu B, Zhu X, Zheng L, Zhang R, Xu T.SEC-10 and RAB-10 coordinate basolateral recycling of clathrin-independent cargo through endosomal tubules in Caenorhabditis elegans.Proc Natl Acad Sci U S A.,2014, [4] Li L, Wan T, Wan M, Liu B, CHeng R, Zhang R.The effect of the size of fluorescent dextran on its endocytic pathway.Cell Biol Int,2015,531-539 [5] Li Y, Cheng D, Cheng R, Zhu X, Wan T, Liu J, Zhang R..Mechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer’s disease amyloid-β proteins.PLoS One,2014,e99939 [6] Boucrot E, Saffarian S, Zhang R, Kirchhausen T.Roles of AP-2 in clathrin-mediated endocytosis.PLos One,2010,e10597 [7] Li Z, Zhou W, Wu ZX, Zhang RY, Xu T.Fabrication of size-controllable ultrasmall-disk electrode: monitoring single vesicle release kinetics at tiny structures with high spatio-temporal resolution.Biosen Bioelectron,2009,1358-1364