个人简介
教育经历 1999年~2003年 北京大学生命科学学院生物科学专业 学士 2003年~2009年 美国西北大学神经科学专业 博士 工作经历 2010年~2014年 美国加州大学旧金山分校神经内科系 博士后
研究领域
(1)研究人类突变影响睡眠或昼夜节律的机理;(2)挖掘和鉴定新的睡眠基因和生物钟基因,研究其调控睡眠或昼夜节律的机理;(3)研究睡眠和生物钟对情绪、学习记忆、新陈代谢等生命过程的影响及调节机理,从而探索睡眠和生物钟的功能。
近期论文
[1] The Cryptochrome Photoreceptor Gates PDF Neuropeptidergic Signaling to Set Circadian Network Hierarchy in Drosophila.Curr Biol,2009,1-6 [2] DN1(p) circadian neurons coordinate acute and PDF inputs to produce robust daily behavior in Drosophila.Curr Biol,2010,591-599 [3] The genetics of the human circadian clock.Adv Genet,2011,231-247 [4] PKCγ Participates in Food Entrainment by Regulating BMAL1.Proc Natl Acad Sci USA,2012,20679-20684 [5] Diversity of Human Clock Genotypes and Consequences.Prog Mol Biol Transl Sci,2013,51-81 [6] Nuclear envelope protein MAN1 regulates clock through BMAL1.Elife,2014,e02981 [7] Nuclear envelope regulates the circadian clock.Nucleus,2015,114-117 [8] Circadian Control of Global Transcription.Biomed Res Int,2015,187809 [9] PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait.Proc Natl Acad Sci USA,2016,E1536-1544 [10] CGDB: a database of circadian genes in eukaryotes.Nucleic Acids Res,2017,D397-403 [11] Bu B,Zhang L.A New Link Between Insulin Signaling and Fragile X Syndrome.Neurosci Bull,2017,118-120 [12] Nuclear Envelope Protein MAN1 Regulates the Drosophila Circadian Clock via Period.Neurosci Bull,2019,969-978