马聪 照片

马聪

教授

所属大学: 华中科技大学

所属学院: 生命科学与技术学院

邮箱:
cong.ma@hust.edu.cn

个人主页:
http://faculty.hust.edu.cn/macong/zh_CN/index.htm

个人简介

教育经历 1996-2000 中南民族大学化学系(本科) 2000-2003 华中科技大学环境科学与工程学院(硕士) 2004-2007华中科技大学生命科学与技术学院(博士) 工作经历 2003-2004 德国慕尼黑大学访问学者 2007-2011美国德州大学西南医学中心博士后 学术兼职 中国生物物理学会 “膜与细胞生物物理分会”委员。

研究领域

大脑思考,学习和记忆的分子基础;突触形成和突触分泌的分子机制;神经系统重要膜蛋白的结构和功能;神经退行性疾病发病机理。

近期论文

[1] Hong Zhang#, Mengshi Lei#, Yu Zhang, Hao Li, Zhen He, Sheng Xie, Le Zhu, Shen Wang, Jianfeng Liu, Yan Li, Youming Lu*, Cong Ma*. Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release. Science Advances. 2024. 10(20):eadi7024. doi: 10.1126/sciadv.adi7024.(#共同第一作者,*通讯作者). [2] Shen Wang, Cong Ma*. A practical guide for fast implementation of SNARE-mediated liposome fusion. Biophysics Reports. 2024. 10(1):31. doi: 10.52601/bpr.2023.230017.(*通讯作者). [3] Fenglei Jian#, Shen Wang#, Rui Tian, Yufen Wang, Chuangpeng Li, Yan Li, Shixuan Wang, Chao Fang, Cong Ma*, Yueguang Rong*. The STX17-SNAP47-VAMP7/VAMP8 complex is the default SNARE complex mediating autophagosome-lysosome fusion. Cell Research. 2024. 34:151-168. doi: 10.1038/s41422-023-00916-x.(#共同第一作者,*通讯作者). [4] Mengshi Lei, Weiyou Wang, Hong Zhang, Jihong Gong, Zhili Wang, Hanmian Cai, Xiaofei Yang, Shen Wang, Cong Ma*. Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation. Cell Reports. 2023. 42(12):113522. doi: 10.1016/j.celrep.2023.113522.(*通讯作者). [5] Qingfang Shao#, Chandra Sugiarto Wijaya#, Shen Wang#, Xinan Meng, Cheng Yuan, Cong Ma*, Suhong Xu*. The SNARE complex formed by RIC-4/SEC-22/SYX-2 promotes C. elegans epidermal wound healing. Cell Reports. 2023. 42(11):113349. doi: 10.1016/j.celrep.2023.113349.(#共同第一作者,*通讯作者). [6] Chuqi Liu#, Dexiang Liu#, Shen Wang, Lu Gan, Xiangliang Yang, Cong Ma*. Identification of the SNARE complex that mediates the fusion of multivesicular bodies with the plasma membrane in exosome secretion. Journal of Extracell Vesicles. 2023. 12(9):12356. doi: 10.1002/jev2.12356.(#共同第一作者,*通讯作者). [7] Li Zhang#, Lei Li#, Ziqing Wei, Hao Zhou, Haowen Liu, Shen Wang, Yijing Ren, Tiankai Dai, Jiafan Wang, Zhitao Hu*, Cong Ma*. The C2 and PH domains of CAPS constitute an effective PI (4, 5) P2-binding unit essential for Ca2+-regulated exocytosis. Structure. 2023. 31(4):424-434. doi: 10.1016/j.str.2023.02.004.(#共同第一作者,*通讯作者). [8] Yan Zhang#, Yaru Hu#, Huayong Xie, Maili Liu, Jun Yang*, Cong Ma*. Structural Mechanism of Soluble N-ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Assembly in Lipid Bilayers Revealed by Solid-State NMR. Journal of the American Chemical Society. 2023. 145(19):10641-10650. doi: 10.1021/jacs.3c00764.(#共同第一作者,*通讯作者). [9] Shen Wang, Cong Ma*. Neuronal SNARE complex assembly guided by Munc18-1 and Munc13-1. FEBS Open Bio. 2022. 12(11):1939-1957. doi: 10.1002/2211-5463.13394.(*通讯作者). [10] Yuanyuan Xu#, Le Zhu#, Shen Wang*, Cong Ma*. Munc18 - Munc13-dependent pathway of SNARE complex assembly is resistant to NSF and α-SNAP. FEBS Journal. 2022. 289(20):6367-6384. doi: 10.1111/febs.16528.(#共同第一作者,*通讯作者). [11] Tianzhi Li, Qiqi Cheng, Shen Wang, Cong Ma*. Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis. Elife. 2022. 11:e79926. doi: 10.7554/eLife.79926.(*通讯作者). [12] Shen Wang, Cong Ma*. Stability profile of the neuronal SNARE complex reflects its potency to drive fast membrane fusion. Biophysical Journal. 2022. 121(16):3081-3102. doi: 10.1016/j.bpj.2022.07.013.(*通讯作者).