李海玲
教授
所属大学: 华中科技大学
所属学院: 化学与化工学院
个人简介
教育经历 1986.9 - 1989.7:重庆钢铁高等专科学校,大学专科毕业。 1996.9 - 1999.5:华中理工大学,研究生毕业,获理学硕士学位。 2002.9 - 2008.6:华中科技大学,研究生毕业,获理学博士学位。 工作经历 1989.7 - 1996.8:南昌硬质合金厂,担任助理工程师。
研究领域
1. 天然产物提取及分析 2. 铁过载损伤机理
近期论文
[1]Huixian Ye, Jun Zhou, Hailing Li*, Zhonghong Gao*. Heme prevents highly amyloidogenic human calcitonin (hCT) aggregation: a potential new strategy for the clinical reuse of hCT. Journal of Inorganic Biochemistry. 2019, 196: 110686. [2]Jiayu Li, Zhen Yang, Hailing Li*, Zhonghong Gao*. Structure effect of water-soluble iron porphyrins on catalyzing protein tyrosine nitration in the presence of nitrite and hydrogen peroxide. Nitric Oxide. 2019, 91:42-51. [3]Xu Fang, Wanxia Gao, Zhen Yang, Zhonghong Gao*, Hailing Li*. Dual anti/pro-oxidant behaviors of flavonoids pertained to Cu (II) catalyzed tyrosine nitration of insulin receptor kinase domain in the anti-diabetic study. Journal of Agricultural and Food Chemistry. 2020, 68(22): 6202-6211. [4]Pengfei Zhang, Lizhen Zeng, Wanxia Gao, Hailing Li*, Zhonghong Gao*. Peroxynitrite scavenger FeTPPS effectively inhibits hIAPP aggregation and protects against amyloid induced cytotoxicity. International Journal of Biological Macromolecules. 2020, 161:336-344. [5]Huixian Ye, Hailing Li*, Zhonghong Gao*Y12 nitration of human calcitonin (hCT): A promising strategy to produce non-aggregation bioactive hCT. Nitric Oxide. 2020, 104-105: 11-19. [6]Jie Zhao, Jinming Wu, Zhen Yang, Lei Ouyang, Lihua Zhu, Zhonghong Gao*, Hailing Li*. Nitration of hIAPP promotes its toxic oligomer formation and exacerbates its toxicity towards INS-1 cells. Nitric Oxide. 2019, 87:23-30. [7]Jie Zhao, Wanxia Gao, Zhen Yang, Hailing Li*, Zhonghong Gao*. Nitration of amyloid-β peptide (1-42) as a protective mechanism for the amyloid-β peptide (1-42) against copper ion toxicity. Journal of Inorganic Biochemistry. 2019, 190:15-23.