1998.09-2002.06 河南师范大学化学与环境科学学院，化学教育专业，理学学士（导师：王玉炉 教授） 2002.09-2005.06 河南师范大学化学与环境科学学院，有机化学专业，理学硕士（导师：李伟 教授） 2005.07-至今 河南师范大学化学化工学院任教，先后任助教、讲师、副教授和硕士生导师 2007.09-2010.12 南开大学化学学院，有机化学专业，理学博士（导师：朱晓晴 教授和程津培 院士） 2014.3-2019.12 河南师范大学化学博士后流动站博士后（合作导师：郭海明 教授） 其中：2014.08-2015.08 受省委组织部派遣河南省博士服务团到许昌豪丰化学科技有限公司挂职副总经理 2017.10-2019.10 借调河南师范大学科技处大健康中心平台秘书 2020.12-至今 河南师范大学化学化工学院产学研中心主任

1、手性核苷类药物的设计与不对称合成研究 2、含氮杂环化合物抗肿瘤、抗病毒活性、构效关系及作用机制研究 3、光催化电催化酶催化不对称合成研究

Xian-Jia Li, Meng-Cheng Zhang, Xiang Li, Lu-Lu Guan, Yu-Ru Liang*, Er-Jun Hao*,Yang Wang,* Hai-Ming Guo*, Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction,J. Med. Chem. 2025, 68, DOI:10.1021/acs.jmedchem.4c02819 Er-Jun Hao,*Yan Zhao, Min Yu, Xian-Jia Li, Ke-Xin Wang, Fu-Ying Su, Yu-Ru Liang,* Yang Wang,* Hai-Ming Guo*,Discovery, Synthesis and Activity Evaluation of Novel Five-membered Sulfur-containing Heterocyclic Nucleosides as Potential Anticancer Agents in Vitro and in Vivo, J. Med. Chem. 2024, 67, 12553-12570.（国际药学领域顶尖期刊, Highlight by CBG、cDRUGS和X-MOL, Top） Er-Jun Hao, Gong-Xin Li, Yu-Ru Liang, Ming-Sheng Xie, Dong-chao Wang, Xiao-Han Jiang, Jia-Yi Cheng, Zhi-Xian Shi, Yang Wang,* Hai-Ming Guo*;Design, Synthesis, and Activity Evaluation of Novel Acyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo, J. Med. Chem. 2021, 64, 2077-2109. (国际药学领域顶尖期刊, Highlight by CBG和X-MOL, Top, IF8.039) Yuqing Chen;Xin Wang; Jing-Ran Shan; Zhixian Wu, Renxu Cao;Yonghong Liu;Yunhe Jin,Erjun Hao*;K. N. Houk*; Lei Shi* ,Chemoselective Functionalization of Tertiary C-H Bonds of Allylic Ethers: Enantioconvergent Access to sec,tert-Vicinal Diols，Angew. Chem. Int. Ed. 2025,e202501924.(化学领域顶尖期刊，SCI一区，Top，IF16.1) Yuqing Chen; Huaipu Yan; Qian Liao*; Dandan Zhang; Shuangjie Lin;Erjun Hao*; Rukhsana Murtaza;Chenchen Li; Chao Wu; Chunying Duan;Lei shi*;Synthesis of Homoallylic Amines by Radical Allylation of Imines with Butadiene under Photoredox Catalysis，Angew. Chem. Int. Ed. 2022,e202204516.(化学领域顶尖期刊，SCI一区，Top，IF16.823) Yonghong Liu, Zhixian Wu, Jingran Shan*, Huaipu Yan, Er-Jun Hao*, Lei Shi*,Titanium catalyzed [2σ+2π] cycloaddition of bicyclo[1.1.0]-butanes with 1,3-dienes for efficient synthesis of stilbene bioisosteres, Nature Comm. 2024, 15,4374. (化学领域顶尖期刊，SCI一区，Top，IF16.6) Er-Jun Hao, Dan-Dan Fu, Dong-Chao Wang*, Tao Zhang, Gui-Rong Qu，Gong-Xin Li，Yu Lan*, Hai-Ming Guo*，Chemoselective Asymmetric Dearomative [3+2] Cycloaddition Reactions of Purines with Aminocyclopropanes， Org. Chem. Front. 2019,6,863-867. (SCI一区，Top, IF5.456) Er-Jun Hao, Gong-Xin Li, Zhen-Zhen Lv, Fu-Sheng Li, Yu-Qing Chen, Shuang-Jie Lin, Cai-Zhe Shi, and Lei Shi*，“In-Situ Immobilization” of Multicomponent Chiral Catalyst (MCC) via Non-covalent Interactions for Heterogeneous Asymmetric Hydrogenation Reactions，Org. Chem. Front. 2020, 7, 345-349. (SCI一区，Top, IF5.456) Erjun Hao*, Binghui Lu，Yonghong Liu, Tianxiao Yang, Huaipu Yan, Xiaobo Ding, Yunhe Jin, Lei Shi*，Difunctionalization of 1,3-Butadiene via Sequential Radical Thiol-ene Reaction and Allylation by Dual Photoredox and Titanium Catalysis，Org. Lett. 2023, 25(27), 5094-5099.(SCI一区，Top，IF5.2) Huaipu Yan, Dandan Zhang, Yonghong Liu, Xin Wang, Zhixian Wu, Yunhe Jin, Xiaobo Ding, Jingran Shan, Erjun Hao*, Lei Shi*； Photoredox chromium and cobalt dual catalysis for carbonyl allylation with butadiene via allyl radical intermediates,Org. Chem. Front. 2024,11, 684-689. (SCI一区，IF=5.4，Top) Huaipu Yan,Jing-Ran Shan,Fengzhi Zhang, Yuqing Chen, Xinyi Zhang, Qian Liao, Erjun Hao*, Lei Shi*; Radical Crotylation of Aldehydes with 1,3-Butadiene by Photoredox Cobalt and Titanium Dual Catalysis，Org. Lett. 2023, 25,7694-7699.(SCI一区，Top，IF5.2) Shuang-Jie Lin, Yu-Qing Chen, Huai-Pu Yan, Yong-Hong Liu, Yu-Chen Sun, Er-Jun Hao*, Cai-Zhe Shi, Dan-Dan Zhang, Nan Zhu, and Lei Shi*；Activation of Chromium Catalysts by Photoexcited Hantzsch Ester for Decarboxylative Allylation of Aldehydes with Butadiene，Org. Lett. 2021, 23(20), 8077–8081.(SCI一区，Top，IF6.072) Yonghong Liu,Huaipu Yan, Yuqing Chen, Erjun Hao,* Lei Shi,* Photoinduced copper-catalyzed selective three-component 1,2-amino oxygenation of 1,3-dienes, Chem.Comm. 2023,59,10388-10391. (SCI二区，IF4.9) Jie Ma, Rong Feng, Hao-Lin Zhou, Er-Jun Hao*, Zhen Shi, and Zhi-Bing Dong*,One Pot Synthesis of N,N-diphenyl-2-benzothiazolamines from 1-(2-Iodophenyl)-3-phenylthioureas and Iodobenzenes, J. Org. Chem. 2022, 87(21), 14342–14351. (SCI二区，IF4.198) Xi Wang, Jin-Quan Chen, Xing-Xing Yang, Er-Jun Hao*, Zhi-Bing Dong*,Synthesis of Diaryl Sulfides by Using Tetramethylthiuram Monosulfide (TMTM) as Organosulfur Source: a Practical C(sp2)-S Bond Construction, Eur. J. Org. Chem. 2022,e202200015.(IF3.261) Yue-Xiao Wu; Kang Peng, Zhi-Chao Hu, Yong-Hao Fan, Zhen Shi; Er-Jun Hao*; Zhi-Bing Dong*; Iodine-mediated cross dehydrogenation coupling of heterocyclic thiols with amines: an easy and practical formation of S-N bond, Eur. J. Org. Chem. , 2021,43: 5889-5894. (IF3.261) Pei-Hua Zhao*, Kuan-Kuan Xiong, Wen-Jun Liang, Er-Jun Hao*，Synthesis, crystal structures and electrocatalytic properties of bridgehead-C- functionalized diiron dithiolate complexes，J. Coord. Chem. 2015, 68,968-979. Gao, Chun; Liu, xin; Wang, Minghui; Liu, Shuxian; Zhu, Tingting; Zhang, Yikang; Hao, Erjun*; Yang, Qiliang*;Advances in Electrochemical Asymmetric Synthesis，Chin.J.Org.Chem. 2024,44,673-727. Hao, Erjun*, Ding, Xiaobo, Wang, Kexin, Zhou, Honghao, Yang, Qiliang, Shi, Lei*. Recent Progress on [3+2] Ring-Expansion Reaction of Aziridines with Unsaturated Compounds[J]. Chinese Journal of Organic Chemistry,Chin.J.Org.Chem. 2023, 43：4057-4074. Er-Jun Hao, Qing Zhang, Qi-Ying Zhang*,Gui-Rong Qu, Xi-Ning Yang, Hai-Ming Guo*, Efficient Synthesis of Spirocyclic Nucleosides via Michael-initiated Intermolecular Cyclopropanation Reaction, Chin.J.Org.Chem. 2019, 39,3237-3243. Er-Jun Hao, Xiao-Han Jiang, Dan-Dan Fu, Dong-Chao Wang*, Ming-Sheng Xie, Hai-Ming Guo, Synthesis of 3-Cyanomethyl Oxoindoles via Palladium- catalyzed Domino Heck/Cyanation Reaction in Water, Chin.J.Org. Chem. 2016, 36, 2746-2751.