娄文勇
教授 博导 硕导
个人简介
娄文勇,教授、“全国百篇优秀博士学位论文“作者、国家优秀青年科学基金(优青,首届)”获得者、广东省高等学校“千百十工程”国家级培养对象、广东省特支计划百千万工程领军人才以及教育部新世纪优秀人才;现为华南理工大学食品科学与工程学院副院长。1999年本科毕业于湖北工业大学生物工程专业,2002年硕士毕业于华南理工大学发酵工程专业,2005年博士毕业于华南理工大学生物化工专业,曾在英国华威大学(Warwick University)进行合作研究。近年来主要从事食品生物技术、生物催化等学科的基础与应用研究。在新型高效生物催化剂的筛选与改造、离子液体中生物催化、手性药物及其中间体的不对称生物合成、生物质的高效利用与转化方面有较深厚的研究工作积累,取得一系列有影响的创新科研成果。在ChemSusChem, Journal of Agricultural & Food Chemistry, Bioresource Technology, Green Chemistry,Chemical Engineering Science等该领域的重要学术刊物上发表了SCI论文90余篇,研究工作受同行的高度评价,被众多学术权威发表于Chemical Reviews(等刊物的论文正面引用。为多个国际学术刊物如Bioresource Technology, Journal of Biotechnology等的兼职审稿人。
科研项目 1. 国家自然科学基金面上:深度共熔溶剂中环氧化物水解酶催化环氧化物不对称水解反应的研究,21676104 2. 国家优秀青年科学基金:新型非水介质中生物催化及生物质转化,21222606 3. 国家自然科学基金面上:含新型离子液体介质微生物细胞催化烯烃不对称环氧化反应的研究,21376096 4. 国家自然科学基金重点:基于离子液体的生物质转化关键科学问题,21336002 5. 广东省自然科学基金重点:含离子液体介质中生物催化烯烃不对称环氧化反应的研究,S2013020013049 6. 广东省科技计划项目:新型糖固体酸催化剂的制备及其生产生物柴油的关键技术研究, 2009B030801004 7. 中央高校基本科研业务费重点:新型离子液体中酶促外消旋酮基布洛芬(酯)不对称转化的研究,2013ZG0003 8. 广州潮徽化工科技有限公司(企事业单位委托):华南理工大学-潮徽绿色精细化工技术联合创新研究中心,D8132690
1.2015年获得广东省“特支计划”百千万工程领军人才 2.2014年获得广东省科学技术二等奖(自然科学类)(排名第二) 3.2014年入选广东省高等学校“千百十”人才工程第八批国家级培养对象 4.2012年获得国家优秀青年科学基金(首届优青) 5.2012年获得中国轻工业联合会“十一五”科技创新先进个人奖 6.2012年入选华南理工大学杰出人才(优秀青年学者)首批培养对象 7.2010年获得教育部新世纪优秀人才 8.2009年获得全国百篇优秀博士学位论文奖
研究领域
食品生物技术
近期论文
1. Cao S.L., Yue D.M., Li X.H., Smith T.J., Li N., Zong M.H., Wu H., Ma Y.Z., Lou W.Y.* Novel nano-/micro-biocatalyst: soybean epoxide hydrolase immobilized on UiO-66-NH2 MOF for efficient biosynthesis of enantiopure (R)-1, 2-octanediol in deep eutectic solvent. ACS Sustainable Chemistry & Engineering, 2016, 4: 3586−3595 2. Wei P., Gao J.X., Zheng G.W., Wu H., Zong M.H., Lou W.Y.* Engineering of a novel carbonyl reductase with coenzyme regeneration in E. colifor efficient biosynthesis of enantiopure chiral alcohols. Journal of Biotechnology, 2016,230: 54-62 3. Xu P., Du P.X., Zong M.H., Li N., Lou W.Y.* Combination of deep eutectic solvent and ionic liquid to improve biocatalytic reduction of 2-octanone with Acetobacter pasteurianus GIM1.158 cell. Scientific Reports, 2016, 6:26518 4. Xu P., Zheng G.W., Du P.X., Zong M.H., Lou W.Y.* Whole-cell biocatalytic processes with ionic liquids. ACS Sustainable Chemistry & Engineering, 2016, 4, 371−386 5. Cao S.L., Huang Y.M., Li X.H., Xu P., Wu H., Li N., Lou W.Y.*, Zong M.H. Preparation and characterization of immobilized lipase from Pseudomonas cepacia onto magnetic cellulose nanocrystals. Scientific Reports, 2016, 6:20420 6. Wei P., Liang J., Cheng J., Zong M.H., Lou W.Y.* Markedly improving asymmetric oxidation of 1-(4-methoxyphenyl) ethanol with Acetobacter sp. CCTCC M209061 cells by adding deep eutectic solvent in a two-phase system. Microbial Cell Factories, 2016, 15:5 7. Deng X., Cao S.L., Li N., Wu H., Smith T.J., Zong M.H., Lou W.Y.* A magnetic biocatalyst based on mussel‐inspired polydopamine and its acylation of dihydromyricetin. Chinese Journal of Catalysis, 2016, 37: 584-595 8. Zhao B.Y., Xu P. Yang F.X., Wu H., Zong M.H., Lou W.Y.*Biocompatible deep eutectic solvents based on choline chloride: characterization and application to the extraction of rutin from Sophora japonica. ACS Sustainable Chemistry & Engineering, 2015, 3:2746−2755 9. Cao S.L., Xu H., Li X.H., Zong M.H., Lou W.Y.*Papain@magnetic nanocrystalline cellulose nanobiocatalyst: a highly efficient biocatalyst for dipeptide biosynthesis in deep eutectic solvents. ACS Sustainable Chemistry & Engineering, 2015, 3:1589−1599 10. Wei P., Xu P., Wang X.T., Lou W.Y.*, Zong M.H. Asymmetric reduction of ethyl acetoacetate catalyzed by immobilized Acetobacter sp. CCTCC M209061 cells in hydrophilic ionic liquid hybrid system. Biotechnology and Bioprocess Engineering, 2015, 20: 324-332 11. Hu T.G., Cheng J.H., Zhang B.B., Lou W.Y.*, Zong M.H. Immobilization of alkaline protease on amino-functionalized magnetic nanoparticles and its efficient use for preparation of oat polypeptides. Industrial & Engineering Chemistry Research, 2015, 54: 4689−4698 12. Xu P., Xu Y., Li X.F., Zhao B.Y., Z ong M.H., Lou W.Y.* Enhancing asymmetric reduction of 3‑chloropropiophenone with immobilized Acetobacter sp. CCTCC M209061 cells by using deep eutectic solvents as cosolvents. ACS Sustainable Chemistry & Engineering, 2015, 3: 718−724 13. Li W., Wu H., Liu B., Hou X.D., Wan D.J., Lou W.Y.*, Zhao J.* Highly efficient and regioselective synthesis of dihydromyricetinesters by immobilized lipase. Journal of Biotechnology, 2015,199: 31-37 14. Xu P., Cheng J., Lou W.Y.*, Zong M.H. Using deep eutectic solvents to improve the resolution of racemic 1-(4-methoxyphenyl)ethanol through Acetobacter sp. CCTCC M209061 cellmediated asymmetric oxidation. RSC Advances, 2015, 5: 6357-6364
15. Cao S.L., Li X.H., Lou W.Y.*, Zong M.H.* Preparation of a novel magnetic cellulose nanocrystal and its efficient use for enzyme immobilization. Journal of Materials Chemistry B, 2014, 2: 5522–5530
16. Hu S.L.,Smith T.J., Lou W.Y.*, Zong M.H. Efficient hydrolysis of cellulose over a novel sucralose-derived solid acid with cellulose- binding and catalytic sites. Journal of Agricultural & Food Chemistry, 2014, 62: 1905−1911 17. Yu C.Y., Wei P., Li X.F., Zong M.H., Lou W.Y.* Using ionic liquid in a biphasic system to improve asymmetric hydrolysis of styrene oxide catalyzed by cross-linked enzyme aggregates (CLEAs) of mung bean epoxide hydrolases. Industrial & Engineering Chemistry Research, 2014, 53: 7923−7930 18. Du P.X., Wei P., Lou W.Y.* Zong M.H. Biocatalytic anti-Prelog reduction of prochiral ketones with whole cells ofAcetobacter pasteurianus GIM1.158. Microbial Cell Factories 2014, 13: 84 19. Huang C., Li Y.Y., Liu L.P., Wu H.*, Zong M.H.,Lou W.Y.* Kinetics and mechanism analysis on microbial oil production by Trichosporonfermentans in rice straw hydrolysate. Industrial & Engineering Chemistry Research, 2014, 53:19034-19043 20. Li Y. , Hu S.L, Cheng J.H.* , Lou W.Y.*Acidic ionic liquid‐catalyzed esterification of oleic acid for biodieselsynthesis. Chinese Journal Catalysis, 2014, 35, 396–406 21. Lou W.Y.*, Guo Q., Chen W.J., Zong M.H.*, Smith T.J. A highly active bagasse-derived solid acid catalyst with properties suitable for production of biodiesel. ChemSusChem, 2012,5:1533-1541 22. Chen W.J.,Lou W.Y.*, Zong M.H.*. Efficient asymmetric hydrolysis of styrene oxide catalyzed by Mung bean epoxide hydrolases in ionic liquid-based biphasic systems. Bioresource Technology, 2012, 115:58-62 23. Xiao Z.J., Du P.X.,Lou W.Y.*, Wu H., Zong M.H.* Using water-miscible ionic liquids to improve the biocatalytic anti-Prelog asymmetric reduction of prochiral ketones with whole cells of Acetobacter sp. CCTCC M209061. Chemical Engineering Science, 2012, 84, 695-705