教育背景 2010.09−2015.07 吉林大学，化学学院，超分子结构与材料国家重点实验室，高分子化学与物理专业，理学博士（导师：吴立新教授） 2006.09−2010.07 吉林大学，化学学院，化学专业，理学学士 工作履历 2021.01−至今 湖南大学化学化工学院，副教授 2016.04−2020.09 耶路撒冷希伯来大学从事博士后研究（合作教授：Itamar Willner院士） 2015.08−2016.03 吉林大学，化学学院，研究助理（合作教授：吴立新教授）

非平衡态人工信号转导网络：细胞通过复杂的信号转导网络来实现对外界刺激信号的转化与传递，调控相应细胞功能，决定细胞命运。我们重点聚焦生命体系中信号转导网络的化学重构与功能模拟研究，探索信号转导网络的形成过程及其信号转导机制，发展非平衡态人工信号转导网络工具，构建具有复杂信号处理与转导功能的人工细胞，以调控生物体的重要生命活动

Si Chen, Weijun Shu, Shan Wang,* Liang Yue,* Weihong Tan,* Bioinspired Nucleic Acid-Based Bandpass Filters and Their Concentration-Adaptive Functions. J. Am. Chem. Soc. 2025, 147, 12786–12799. (IF: 14.612) Liang Yue, Shan Wang, Weihong Tan,* Chapter 1: Developing DNA Aptamer Toolbox for Cell Research. Wiley-VCH GmbH, 2024. Sivan Lilienthal, Guo-Feng Luo, Shan Wang, liang Yue, Amit Fischer, Avner Ehrlich, Yaakov Nahmias, Itamar Willner,* Constitutional Dynamic Networks-Guided Synthesis of Programmed “Genes”, Transcription of mRNAs, and Translation of Proteins. J. Am. Chem. Soc. 2020, 142, 21460-21468. (IF: 14.612) Liang Yue,# Shan Wang#, Zhixin Zhou, Itamar Willner,* Nucleic acid-Based Constitutional Dynamic Networks: From Basic Principles to Applications. J. Am. Chem. Soc. 2020, 142, 21577–21594. (#Equal contribution, IF: 14.612) Shan Wang, Liang Yue, Verena Wulf, Sivan Lilienthal, Itamar Willner,* Dissipative Constitutional Dynamic Networks for Tunable Transient Responses and Catalytic Functions. J. Am. Chem. Soc. 2020, 142, 17480–17488. (IF: 14.612) Shan Wang, Liang Yue, Itamar Willner,* Enzyme-Guided Selection and Cascaded Emergence of Nanostructured Constitutional Dynamic Networks. Nano Lett. 2020, 20, 5451−5457. (IF: 11.238) Liang Yue,# Shan Wang#, Itamar Willner,* Three-Dimensional Nucleic Acid-Based Constitutional Dynamic Networks: Enhancing Diversity through Complexity of the Systems. J. Am. Chem. Soc. 2019, 141, 16461−16470. (#Equal contribution, IF: 14.612) Shan Wang,# Liang Yue,# Zi-yuan Li, Junji Zhang, He Tian, Itamar Willner,* Light‐Induced Reversible Reconfiguration of DNA‐Based Constitutional Dynamic Networks: Application to Switchable Catalysis. Angew. Chem. Int. Ed. 2018, 57, 8105−8109. (#Equal contribution, IF: 12.959) Liang Yue,# Shan Wang#, Sivan Lilienthal, Verena Wulf, Françoise Remacle, R. D. Levine, Itamar Willner,* Intercommunication of DNA-Based Constitutional Dynamic Networks. J. Am. Chem. Soc. 2018, 140, 8721−8731. (#Equal contribution, IF: 14.612) Shan Wang,# Liang Yue,# Zohar Shpilt, Alessandro Cecconello, Jason S Kahn, Jean-Marie Lehn, Itamar Willner,* Controlling the Catalytic Functions of DNAzymes within Constitutional Dynamic Networks of DNA Nanostructures. J. Am. Chem. Soc. 2017, 139, 9662−9671. (#Equal contribution, IF: 14.612) Shan Wang, Rémi Cazelles, Wei-Ching Liao, Margarita Vázquez-González, Amani Zoabi, Raed Abu-Reziq, Itamar Willner,* Mimicking Horseradish Peroxidase and NADH Peroxidase by Heterogeneous Cu2+-Modified Graphene Oxide Nanoparticles. Nano Lett. 2017, 17, 2043−2048. (IF: 11.238) Shan Wang, Haolong Li,* Dan Li, Tianyang Xu, Shilin Zhang, Xiaoyuan Dou, Lixin Wu,* Noncovalent Functionalization of Graphene Nanosheets with Cluster-Cored Star Polymers and Their Reinforced Polymer Coating. ACS Macro Lett. 2015, 4, 974−978. (IF: 6.042) Shan Wang, Haolong Li,* Liying Zhang, Bao Li, Xiao Cao, Guohua Zhang, Shilin Zhang, Lixin Wu,* Phase Transfer and Dispersion of Reduced Graphene Oxide Nanosheets Using Cluster Suprasurfactants. Chem. Commun. 2014, 50, 9700−9703. (IF: 5.996) Shan Wang, Haolong Li,* Shuang Li, Fang Liu, Dongqing Wu, Xinliang Feng, Lixin Wu,* Electrochemical-Reduction-Assisted Assembly of a Polyoxometalate/Graphene nanocomposite and Its Enhanced Lithium-Storage Performance. Chem. Eur. J. 2013, 19, 10895–10902. (IF: 4.857) Liang Yue, Shan Wang, Itamar Willner,* Functional Constitutional Dynamic Networks Revealing Evolutionary Reproduction/Variation/Selection Principles. J. Am. Chem. Soc. 2020, 142, 14437−14442. (IF: 14.612) Liang Yue, Shan Wang, Verena Wulf, Itamar Willner,* Stiffness-Switchable DNA-Based Constitutional Dynamic Network Hydrogels for Self-Healing and Matrix-Guided Controlled Chemical Processes. Nat. Commun. 2019, 10, 4774. (IF: 12.121) Liang Yue, Shan Wang, Itamar Willner,* Triggered Reversible Substitution of Adaptive Constitutional Dynamic Networks Dictates Programmed Catalytic Functions. Sci. Adv. 2019, 5, eaav5564. (IF: 13.116) Liang Yue, Shan Wang, Verena Wulf, Sivan Lilienthal, Françoise Remacle, R. D. Levine,* Itamar Willner,* Consecutive Feedback-driven Constitutional Dynamic Networks. Proc. Natl. Acad. Sci. U.S.A. 2019, 116, 2843−2848. (IF: 9.412) Liang Yue, Verena Wulf, Shan Wang, Itamar Willner,* Evolution of Nucleic-Acid-Based Constitutional Dynamic Networks Revealing Adaptive and Emergent Functions. Angew. Chem. Int. Ed. 2019, 58, 12238–12245. (IF: 12.959) Zhixin Zhou, Liang Yue, Shan Wang, Jean-Marie Lehn, Itamar Willner,* DNA-Based Multiconstituent Dynamic Networks: Hierarchical Adaptive Control over the Composition and Cooperative Catalytic Functions of the Systems. J. Am. Chem. Soc. 2018, 140, 12077−12089. (IF: 14.612) Jianbang Wang, Liang Yue, Shan Wang, Itamar Willner,* Triggered Reversible Reconfiguration of G-Quadruplex-Bridged “Domino”-Type Origami Dimers: Application of the Systems for Programmed Catalysis. ACS Nano 2018, 12, 12324−12336. (IF: 14.588) Jianbang Wang, Zhixin Zhou, Liang Yue, Shan Wang, Itamar Willner,* Switchable Triggered Interconversion and Reconfiguration of DNA Origami Dimers and Their Use for Programmed Catalysis. Nano Lett. 2018, 18, 2718−2724. (IF: 11.238)