EDUCATION 1994-1998 B.Sc. in Chemistry with first-class honors at National University of Singapore. 1998-2000 M.Sc. in Chemistry at National University of Singapore. Supervisor: Teck-Peng Loh 2000-2005 Ph.D. in Organic Chemistry at Massachusetts Institute of Technology. Supervisor: Gregory C. Fu PROFESSIONAL EXPERIENCE 2005-2008 Postdoctoral researcher at Yale University and University of Illinois at Urbana. Supervisor: John F. Hartwig 2008-2013 Singapore National Research Foundation Fellow (joint appointment) 2008-2019 Assistant Professor and Senior Research Scientist at Nanyang Technological University 2019 Associated Professor at Peking University Shenzhen Graduate School HONORS AND AWARDS 2008 Singapore National Research Foundation fellowship 2011-14 Asian Core Program Lectureship Award (2011 Malaysia, 2012 Taiwan, 2013 Japan and 2014 China) 2012 Thieme Chemistry Journals Award 2015 SPMS Young Researcher Award, Nanyang Technological University 2013, 2017 GSK-EDB Green and Sustainable Manufacturing Award 2019 Bayer Investigator Award

Other research interest includes: 1) Application of photocatalysis and reactive radical species in metal catalysis. 2) Replacement of expensive noble metals with Earth-abundant late 3d metals. 3) Stereoselective formation of strained rings, deuterated and fluorinated compounds, which are becoming increasingly important in medicines. Currently, ongoing projects (2024) in our lab include: 1) nickel and cobalt-catalyzed reductive (conjugate) addition reactions of aldehydes, ketones and Michael acceptors 2) palladium- and nickel-catalyzed Heck arylation and radical alkylation reaction 3) nickel-catalyzed transfer hydrogenation

New Reactivity of Late 3d Metal Complexes in Catalytic Reactions of Alkynes. Shenghan Teng,* Peiyao Liang, Jianrong Steve Zhou*Chem. Soc. Rev. 2025, online. Published on Feb 19, 2025. DOI: 10.1039/D4CS01130A Nickel Complex-Catalyzed Asymmetric Synthesis of Chiral Benzylic Amines: Evolution from Reductive Amination to Borrowing Hydrogen Reaction. Xiuhua Wang and Jianrong Steve Zhou* Chin. Chem. Lett. 2025, under review Unusual 1,1-Dicarboxylation Selectivity in the Domino Hydrocarboxylation of Alkynes with Formate and Application in Polyimides Photoresist.Yaxin Sun; Peng Yang,* Jianbiao Liu; Pin Liu; Xu Wang; Jianrong Steve Zhou,* Bo Tang* Angew. Chem., Int. Ed. 2025, accepted on Feb 28, 2025. doi: 10.1002/anie.202502920 New chemistry of alkynyl trifluoroborates under transition metal-free conditions (review). Shenghan Teng,* Jianrong Steve Zhou* and Wei Huang* Org. Chem. Front. 2024, 11, 5985-6003. Published on Aug 28, 2024. doi: 10.1039/D4QO01398K Nonactivated Aziridine Synthesis by Intermolecular Polarity-Mismatched Carboamination of Unactivated Alkenes with Unactivated Alkyl Halides. Wu, Linlin; Li, Lei; Zhao, Yao; Rui, Jiacheng; Zhan, Ying; Zhang, Ling; Chen, Rizhi; Zhou, Jianrong Steve; Zhu, Chenjie; Wu, Xiaojin* Org. Let. 2024, 26, 5609-5613. Published on Jul 12, 2024. doi: 10.1021/acs.orglett.4c01224 Cobalt-Catalyzed Enantioselective Reductive Arylation, Heteroarylation and Alkenylation of Michael Acceptors via an Elementary Mechanism of 1,4-Addition. Mengxin Zhao, Wenqiang Xu, Yun-Dong Wu, Xiuying Yang, Jianchun Wang, and Jianrong Steve Zhou* J. Am. Chem. Soc. 2024, 146, 20477–20493. Publication on July 10, 2024 https://doi.org/10.1021/jacs.4c06735 Nickel-catalyzed hydrodefluorination/deuterodefluorination of CF3-alkenes with formic acid. Peng Yang,* Haiping Yu, Runze Zhai, Jianrong Steve Zhou,* Bo Tang* Chem. Commun. 2024, 60, 6548-6551. Published on May 29, 2024. Nickel-Catalyzed Enantioselective Reductive Arylation of Common Ketones. Huang Shuai and Jianrong Steve Zhou. J. Am. Chem. Soc. 2024, 146, 12895–12900. doi: 10.1021/jacs.4c02818 Published on May 2, 2023. One of the most read JACS articles of the month. Enantioselective Reductive Alkenylation of a,b-Unsaturated Ketones and Amides via Nickel Catalysis. Mengxin Zhao, Luoqiang Zhang and Jianrong Steve Zhou* ACS Catal. 2024, 14, 6228–6235. doi: 10.1021/acscatal.4c01263. Published on April 10, 2024 Nickel-Catalyzed Enantioselective Reductive Amination of Benzylic Ketones in Alcohols. Xiuhua Wang and Jianrong Steve Zhou* Sci. Chin. Chem. 2024, 67, 2566–2570 Doi: 10.1007/s11426-024-2019-1 Published on March 19, 2024 Hydrogen Bond Enhanced Enantioselectivity in the Nickel-Catalyzed Transfer Hydrogenation of α-Substituted Acrylic Acid with Formic acid. Yaxin Sun, Chao Wang, Peng Yang*, Jie-Yu Yue, Chang Xu, Jianrong Steve Zhou*, and Bo Tang* ACS Catal. 2023, 13, 14213–14220. Doi: 10.1021/acscatal.3c04187. Publication Date: October 21, 2023 Cobalt-Catalyzed Enantioselective Cross-Electrophile Couplings: Stereoselective Syntheses of 5-7 Membered Azacycles. Zhaoming Ma, Wenqiang Xu, Yun-Dong Wu, and Jianrong Steve Zhou* J. Am. Chem. Soc. 2023, 145, 16464–16473 doi: 10.1021/jacs.3c02829 Published on July 21, 2023. Highlighted by Synfacts 2023, 19, 1006. Regioselective and Geometrically Controlled Heck 1,1-Diarylation of Unactivated Aliphatic Alkenes. Yao Zhao, Shuangqiang Wang, Huihui Shao, Xuyong Tan, Rizhi Chen, Teck-Peng Loh, Jianrong Steve Zhou, and Xiaojin Wu* Org. Lett. 2023, 25, 4258-4263 DOI: 10.1021/acs.orglett.3c01214 Published on June 5, 2023 Catalytic Enantioselective Domino Alkenylation-Alkynylation of Alkenes: Stereoselective Syntheses of 5-7 Membered Azacycles and Carbocycles. Zhaoming Ma, Lantian Sun and Jianrong Steve Zhou* Sci. China. Chem. 2023, DOI: 10.1007/s11426-023-1552-0 Published on Apr 10, 2023 . Highlighted by x-mol in April 2023 Cobalt-Catalyzed Asymmetric Umpolung Dideuteration of Enamides for Stereoselective Synthesis of a,b-Dideuterated a-Amino Acids. Aibo Li, Xinjian Song, Qiao Ren, Peiwang Bao, Xinyu Long, Fuli Huang, Lvjiang Yuan, Jianrong Steve Zhou* and Xurong Qin* Angew. Chem., Int. Ed. 2023, e202301091. DOI: 10.1002/anie.202301091 First Published on Mar 17, 2023. Highlighted by x-mol in Dec 2022 Enantioselective Domino Alkenylation-Heteroarylation of Olefins: Stereoselective Syntheses of 5-7 Membered Azacycles. Zhaoming Ma, Lantian Sun and Jianrong Steve Zhou* Chem. Sci. 2023, 14, 3010-3017. DOI: 10.1039/d2sc07117g First published on Feb 17, 2023 Nickel-Catalyzed Enantioselective Reductive Arylation and Heteroarylation of Aldimines via an Elementary 1,4-Addition. Luoqiang Zhang, Xiuhua Wang, Maoping Pu, Peng Yang, Yun-Dong Wu, Yonggui Robin Chi and Jianrong Steve Zhou* J. Am. Chem. Soc. 2023, 145(15), 8498–8509. DOI: 10.1021/jacs.3c00548 First published on April 6, 2023. Highlighted by x-mol in April 2023 Pursuing High Efficiency in Photocatalytic Oxidative Couplings of Heteroarenes and Aliphatic C-H bonds. Luoqiang Zhang, Daoyong Zhu, Jingyao Hu, Minjun Feng, Tze Chien Sum, Haoran Sun, Hajime Hirao, Yonggui Robin Chi and Jianrong Steve Zhou* Org. Chem. Front. 2023, 10, 1651-1659. DOI: 10.1039/D2QO01558G First published on Feb 21, 2023 Reductive-Delay Heck 1,1-Diarylation of Terminal Alkenes. Shao, Huihui; Zhao, Yao; Wang, Shuangqiang; Chen, Rizhi; Zhou, Jianrong Steve; Wu, Xiaojin* Org. Lett. 2022, 24(36), 6520–6524. DOI: 10.1021/acs.orglett.2c02416 Published on September 1, 2022 Nickel-Catalyzed Enantioselective Reductive Conjugate Arylation and Heteroarylation via an Elementary Mechanism of 1,4-Addition. Luoqiang Zhang, Mengxin Zhao, Maoping Pu, Zhaoming Ma, Jingsong Zhou, Caiyou Chen, Yun-Dong Wu, Yonggui Robin Chi, Jianrong Steve Zhou*J. Am. Chem. Soc. 2022, 144(44), 20249–20257. DOI: 10.1021/jacs.2c05678 published on Oct 31, 2022. One of the most read JACS articles of the month. Highlighted by x-mol in Dec 2022. Highlighted by Jiao, Tengchao, Yao, Tuanli, Chin. J. Org. Chem. 2022 (highlights) 2022, 42 (12): 4362-4363. DOI: 10.6023/cjoc202200076 Nickel-Catalyzed Chemo- and Regioselective Arylcyanation of β,γ-Unsaturated Amides. Jinghui Hu, Qiang Du, Yao Zhao, Fei Zhang, Rizhi Chen, Jianrong Steve Zhou, Wu, Xiaojin* Org. Lett. 2022, 24(24), 4328–4332. DOI: 10.1021/acs.orglett.2c01360 published on June 10, 2022 Metal-catalyzed asymmetric heteroarylation of alkenes: diverse activation mechanisms. Shenghan Teng, Jianrong Steve Zhou* Chem. Soc. Rev. 2022, 51, 1592-1607. DOI: 10.1039/D1CS00426C published on 15 Feb 2022 Enantioselective Synthesis of Chiral Carboxylic Acids from Alkynes and Formic Acid by Nickel-Catalyzed Cascade. Reactions: Facile Synthesis of Profens. Peng Yang, Yaxin Sun, Kaiyue Fu, Li Zhang, Guang Yang, Jieyu Yue, Yu Ma,* Jianrong Steve Zhou,* Bo Tang* Angew. Chem., Int. Ed. 2021, accepted. DOI: 10.1002/anie.202111778 Nickel-Catalyzed Enantioselective Umpolung Hydrogenation for Stereoselective Synthesis of b-Amido Esters. Jianrong Steve Zhou,* Siyu Guo, Xiaohu Zhao and Yonggui Robin Chi. Chem. Commun. 2021, 57, 11501-11504. DOI: 10.1039/D1CC05257H. Published on Oct 6, 2021 Asymmetric Domino Heck Arylation and Alkylation of Nonconjugated Dienes: Double C–F···Sodium Attractive Noncovalent Interaction. Daoyong Zhu, Wenqiang Xu, Maoping Pu, Yun-Dong Wu, Yonggui Robin Chi and Jianrong Steve Zhou* Org. Lett. 2021, 23(18), 7064–7068. DOI: 10.1021/acs.orglett.1c02457 Published on Sept 1, 2021. Highlighted by ChemBeanGo in September 2021 Nickel-Catalyzed Heck Reaction of Cycloalkenes using Aryl Sulfonates and Pivalates. Jianrong Steve Zhou,* Xiaolei Huang, Shenghan Teng and Yonggui Robin Chi. Chem. Commun. 2021, 57, 3933-3936. DOI: 10.1039/D1CC00634G Published on March 12, 2021 Enantioselective Three-Component Coupling of Heteroarenes, Cycloalkenes and Propargylic Acetates. Shenghan Teng, Yonggui Robin Chi and Jianrong Steve Zhou* Angew. Chem., Int. Ed.2021, 60(9), 4491-1195. DOI: 10.1002/anie.202014781 First published on 1 Dec 2020. Published on Feb 23, 2021. Highlighted by x-mol in Dec 2020 Enantioselective Intermolecular Heck and Reductive Heck Reactions of Aryl Triflates, Mesylates and Tosylates Catalyzed by Nickel. Xiaolei Huang, Shenghan Teng, Yonggui Robin Chi, Wenqiang Xu, Maoping Pu, Yun-Dong Wu and Jianrong Steve Zhou* (WX, MP and TDW contributed DFT calculation) Angew. Chem., Int. Ed. 2021, 60(6), 2828-2832. DOI: 10.1002/anie.202011036 Published on 2 Nov 2020. Highlighted by chem-station in Nov 2020 Nickel-catalyzed C-alkylation of thioamide, amides and esters by primary alcohols through a hydrogen autotransfer strategy. Peng Yang,* Xiuhua Wang, Yu Ma, Li Zhang, Yaxin Sun, Jieyu Yue, Kaiyue Fu, Jianrong Steve Zhou* and Bo Tang* Chem. Commun. 2020, 56, 14083-14086 DOI: 10.1039/D0CC06468H. First published on 15 Oct 2020 Asymmetric Reductive and Alkynylative Heck Bicyclization of Enynes to Access Conformationally Restricted Aza[3.1.0]bicycles. Xiaolei Huang, Minh Hieu Nguyen, Maoping Pu, Luoqiang Zhang, Yonggui Robin Chi, Yun-Dong Wu and Jianrong Steve Zhou* (MP and TDW contributed DFT calculation) Angew. Chem., Int. Ed. 2020, 59(27), 10814-10818. DOI: 10.1002/anie.202000859 First published on Mar 26, 2020. Highlighted in Synfacts 2020, 16(09), 1078 and Organic Chemistry Portal in Dec 2020 "Metal-Mediated C-C Ring Construction" Asymmetric Three-Component Heck Arylation/Amination of Nonconjugated Cyclodienes. Daoyong Zhu, Zhiwei Jiao, Yonggui Robin Chi, Théo P. Gonçalves, Kuo-Wei Huang and Jianrong Steve Zhou* (TG and KWH contributed DFT calculation) Angew. Chem., Int. Ed. 2020, 59(13), 5341-5345. DOI: 10.1002/anie.201915864 published on Mar 23, 2020 Highlighted by x-mol.com in 2020. Asymmetric Umpolung Hydrogenation and Deuteration of Alkenes by Nickel Catalysts. Siyu Guo, Xiuhua Wang and Jianrong Steve Zhou* Org. Lett. 2020, 22(3), 1204-1207. DOI: 10.1021/acs.orglett.0c00112 published on 15 Jan 2020 Asymmetric Wacker-Type oxyallenylation and Azaallenylation of Cyclic Alkenes. Shenghan Teng, Zhiwei Jiao, Yonggui Robin Chi and Jianrong Steve Zhou* Angew. Chem., Int. Ed. 2020, 59(6), 2246-2250. DOI: 10.1002/anie.201911961 published on Feb 3, 2020