王永中
教授 博士生导师
所属大学: 安徽大学
所属学院: 生命科学学院
邮箱:
yongzhong00@126.com
yzwang@ahu.edu.cn
个人主页:
http://life.ahu.edu.cn/2017/1108/c10934a101697/page.htm
个人简介
王永中,博士,教授,博士生导师。1997年毕业于安徽大学微生物学专业,2003年毕业中国药物科大学微生物与生化药学专业,2007年毕业于复旦大学药剂学专业。2010年7月至2015年1月先后在美国Auburn University药学院、University of Tennessee at Knoxville生物医学工程系、Ohio State University生物医学工程系与Wexner医学中心从事博士后及访问研究。
研究领域
主要有:(1)分子与药物微生物学、(2)药物生物技术与(3)纳米生物技术。在药物发现、药物设计、药物递送、靶向治疗、疾病诊断、纳米生物材料以及医学微生态学等领域从事基础科学研究与应用技术转化。
近期论文
(1)Wang Y, Yu L, Kong X, Sun L. Application of nanodiagnostics inpoint-of-care tests for infectious diseases, International Journal of Nanomedicine, 2017, 12:4789-4803
(2)Hu X, Liu L, Chen D, Wang Y, Zhang J, Shao L, Co-expression of the recombined alcoholdehydrogenase and glucose dehydrogenase and cross-linked enzyme aggregatesstabilization, Bioresource Technology,2017, 224:531-535
(3)Wang Y*, Fan Z, Shao L, Kong X, Hou X, Tian D, Sun Y, Xiao Y,Yu L. Nanobody-derived nanobiotechnology tool kits for diverse biomedical andbiotechnology applications, InternationalJournal of Nanomedicine,2016, 11:3287-3303. (*corresponding author)
(4)Gan X, Zhang X, Cheng Z, Chen L, Ding X, DuJ, Cai Y, Luo Q, Shen J, Wang Y*, YuL*. Toxoplasma gondii inhibitsdifferentiation of C17.2 neural stem cells through Wnt/β-catenin signalingpathway, Biochemical and BiophysicalResearch Communications, 2016, 473:187-193. (*corresponding author)
(5)Fan Z, Sun L, Huang Y, Wang Y, Zhang M. Bioinspired fluorescent dipeptide nanoparticlesfor targeted cancer cell imaging and real-time monitoring of drug release, Nature Nanotechnology, 2016, 11:388-394.
(6)Sun L, Huang Y, Bian Z, Petrosino J, Fan Z,Wang Y, Park K, Yue Tao, Schmidt M,Galster S, Ma J, Zhu H, Zhang M. Sundew-Inspired Adhesive Hydrogels Combinedwith Adipose- Derived Stem Cells for Wound Healing, ACS Applied Materials & Interfaces, 2016, 8 (3):2423-2434.
(7)Huang Y, Wang Y, Sun L, Agrawal R, Zhang M. Sundew adhesive: a naturallyoccurring hydrogel, Journal of The RoyalSociety Interface, 2015, 12(107): 20150226.
(8)Huang Y, Wang Y-J, Wang Y, Yi Si, Fan Z, Sun L, Lin D, Anreddy N, Zhu H, Schmidt M, ChenZ-S, Zhang M. Exploring naturally occurring ivy nanoparticles as an alternativebiomaterial, Acta biomaterialia, 2015,25: 268-283.
(9)Sun L, Fan Z, Wang Y, Huang Y, Schmidt M, Zhang M. Tunable Synthesis ofSelf-assembled Cyclic Peptide Nanotubes and Nanoparticles, Soft Matter, 2015, 11(19): 3822-3832.
(10)Zhou J, Gan X, Wang Y, Zhang X, Ding X, Chen L, Du J, Luo Q, Wang T, Shen J, andYu L. Toxoplasma gondii prevalent in China induce weaker apoptosis of neuralstem cells C17.2 via endoplasmic reticulum stress (ERS) signaling pathways, Parasites & Vectors, 2015,8(1):73-82.
(11)Wang Y, Yi S, Sun L, Huang Y, Lenaghan SC, and Zhang M.Doxorubicin-loaded Cyclic Peptide Nanotube Bundles Overcome MultidrugResistance in Breast Cancer Cells, Journalof Biomedical Nanotechnology, 2014; 10(3):445-454.
(12)Wang Y, Yi S, Sun L, Huang Y, Zhang M. Charge-selectivefractions of naturally occurring nanoparticles as bioactive nanocarriers forcancer therapy, Acta Biomaterialia,2014, 10(10):4269-4284
(13)Yi S, WangY, Huang Y, Xia L, Sun L, Lenaghan SC, and Zhang M. Tea Nanoparticles forImmunostimulation and Chemo-Drug Delivery in Cancer Treatment, Journal of Biomedical Nanotechnology,2014, 10 (6), 1016-1029
(14)Sun L, Yi S, Wang Y, Pan K, Zhong Q, Zhang M. A Bio-inspired Approach for inSitu Synthesis of Tunable Adhesive, Bioinspiration& Biomimetics, 2014, 9 (1), 016005.
(15)Wang T, Zhou J, Gan X, Wang H, Ding X, ChenL, Wang Y, Du J, Shen J, and Yu L.Toxoplasma Gondii Induce Apoptosis of Neural Stem Cells via EndoplasmicReticulum Stress Pathway, Parasitology,2014, 141(7):988-995
(16)Wang Y, Sun L, Yi S, Huang Y, Lenaghan CS, and Zhang M.Naturally Occurring Nanoparticles from Arthrobotrys oligospora as a PotentialImmunostimulatory and Antitumor Agent, AdvancedFunctional Materials, 2013, 23(17):2175-2184. (The discovery was featured by multiple media and press)
(17)Wang Y, Ding Y, Liu X, Chen L, and Yan W. Bioactive Lipid-basedpH Sensitive Micelles for Co-Delivery of Doxorubicin and Ceramide to OvercomeMultidrug Resistance in Leukemia, PharmaceuticalResearch, 2013, 30(11):2902-2916. (Selectedas a cover picture)
(18)Wang Y*, Zhang Z, Sha X, Han L, and Fang X. Reversal ofPaclitaxel- Chemoresistance by Mixed Pluronic P105/L101 Micelles in HumanOvarian Cancer SKOV-3/PTX Cells, Journalof Drug Delivery Science and Technology, 2013, 23(2), 119-128.(*corresponding author)
(19)Lenaghan SC, Wang Y, Xi N, Fukuda T, Tarn T, Hamel WR, and Zhang M. GrandChallenges in Bioengineered Nanorobotics for Cancer Therapy, IEEE Transactions on Biomedical Engineering,2013, 60(3):667-73.
(20)Chen L, Ding Y, Wang Y, Liu X, Babu RJ, Ravis WR, and Yan W. Co-delivery ofZoledronic Acid and Double-strand RNA from Core-shell Nanoparticles, International Journal of Nanomedicine,2013, 8, 137-145.